KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM175B
All Species:
14.24
Human Site:
S274
Identified Species:
34.81
UniProt:
Q15018
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15018
NP_115558.3
415
46901
S274
S
R
Q
M
P
S
E
S
L
D
P
A
F
S
P
Chimpanzee
Pan troglodytes
XP_508099
925
105851
I576
T
E
Q
I
R
R
E
I
A
A
S
L
H
Q
R
Rhesus Macaque
Macaca mulatta
XP_001083977
424
47899
S283
S
R
Q
M
P
S
E
S
L
D
P
A
F
S
P
Dog
Lupus familis
XP_535051
423
47662
S282
S
R
Q
V
P
S
E
S
L
G
P
A
F
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCJ1
415
46924
S274
S
R
Q
M
P
S
E
S
L
E
P
A
F
S
P
Rat
Rattus norvegicus
Q5I0F1
405
45671
G265
Q
A
Q
A
K
G
A
G
E
K
S
Q
N
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHS0
405
46025
G265
K
Q
H
K
I
S
S
G
G
N
K
D
Q
L
E
Frog
Xenopus laevis
Q6GR31
408
45804
G267
K
L
L
M
E
E
K
G
N
K
V
S
E
D
T
Zebra Danio
Brachydanio rerio
Q1LVP6
391
44617
L251
L
Q
E
D
I
A
Q
L
K
E
A
I
G
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793859
236
26638
S96
I
F
S
G
N
S
T
S
N
L
A
T
H
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
97.1
93.8
N.A.
93.4
29.6
N.A.
N.A.
32.5
33.9
31
N.A.
N.A.
N.A.
N.A.
20.9
Protein Similarity:
100
39.1
97.6
95.5
N.A.
96.3
52
N.A.
N.A.
50.8
49.8
49.8
N.A.
N.A.
N.A.
N.A.
32.5
P-Site Identity:
100
13.3
100
86.6
N.A.
93.3
13.3
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
13.3
N.A.
N.A.
20
20
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
10
10
0
10
10
20
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
20
0
10
0
10
0
% D
% Glu:
0
10
10
0
10
10
50
0
10
20
0
0
10
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
40
0
10
% F
% Gly:
0
0
0
10
0
10
0
30
10
10
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
20
10
0
% H
% Ile:
10
0
0
10
20
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
20
0
0
10
10
0
10
0
10
20
10
0
0
10
0
% K
% Leu:
10
10
10
0
0
0
0
10
40
10
0
10
0
10
0
% L
% Met:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
20
10
0
0
10
0
0
% N
% Pro:
0
0
0
0
40
0
0
0
0
0
40
0
0
0
50
% P
% Gln:
10
20
60
0
0
0
10
0
0
0
0
10
10
10
10
% Q
% Arg:
0
40
0
0
10
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
40
0
10
0
0
60
10
50
0
0
20
10
0
50
0
% S
% Thr:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% T
% Val:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _