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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM175B
All Species:
18.18
Human Site:
Y145
Identified Species:
44.44
UniProt:
Q15018
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15018
NP_115558.3
415
46901
Y145
N
S
T
H
A
L
E
Y
V
L
F
R
P
N
R
Chimpanzee
Pan troglodytes
XP_508099
925
105851
Y145
N
S
T
H
A
L
E
Y
V
L
F
R
P
N
R
Rhesus Macaque
Macaca mulatta
XP_001083977
424
47899
Y154
N
S
T
H
A
L
E
Y
V
L
F
R
P
N
R
Dog
Lupus familis
XP_535051
423
47662
Y153
N
S
T
H
A
L
E
Y
V
L
F
R
P
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCJ1
415
46924
Y145
N
S
T
H
A
L
E
Y
V
L
F
R
P
N
R
Rat
Rattus norvegicus
Q5I0F1
405
45671
E142
L
T
P
S
I
T
T
E
S
C
C
T
H
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHS0
405
46025
E142
L
T
S
S
V
M
T
E
S
C
S
T
Y
R
L
Frog
Xenopus laevis
Q6GR31
408
45804
A142
L
L
L
T
S
N
P
A
T
E
T
K
S
T
H
Zebra Danio
Brachydanio rerio
Q1LVP6
391
44617
N128
N
M
R
K
I
L
S
N
Q
E
L
V
F
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793859
236
26638
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.8
97.1
93.8
N.A.
93.4
29.6
N.A.
N.A.
32.5
33.9
31
N.A.
N.A.
N.A.
N.A.
20.9
Protein Similarity:
100
39.1
97.6
95.5
N.A.
96.3
52
N.A.
N.A.
50.8
49.8
49.8
N.A.
N.A.
N.A.
N.A.
32.5
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
0
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
20
10
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
50
20
0
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
50
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
50
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
30
10
10
0
0
60
0
0
0
50
10
0
0
0
30
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
60
0
0
0
0
10
0
10
0
0
0
0
0
50
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
0
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
50
0
10
50
% R
% Ser:
0
50
10
20
10
0
10
0
20
0
10
0
10
0
0
% S
% Thr:
0
20
50
10
0
10
20
0
10
0
10
20
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
50
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _