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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT2 All Species: 28.79
Human Site: S84 Identified Species: 52.78
UniProt: Q15019 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15019 NP_001008491.1 361 41487 S84 R T V Q I E A S T V E I E E R
Chimpanzee Pan troglodytes Q5R1W1 434 50272 S93 K T V Q V E Q S K V L I K E G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851909 532 59884 S255 R T V Q I E A S T V E I E E R
Cat Felis silvestris
Mouse Mus musculus P42208 361 41507 S84 R T V Q I E A S T V E I E E R
Rat Rattus norvegicus Q91Y81 361 41574 S84 R T V Q I E A S T V E I E E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513259 361 41490 S84 R T V Q I E A S T V E I E E R
Chicken Gallus gallus Q5ZMH1 349 40206 T84 T V Q I E A S T V E I E E R G
Frog Xenopus laevis Q63ZQ1 352 40432 T84 T V E I E A S T V E I E E R G
Zebra Danio Brachydanio rerio A2BGU8 361 40623 V120 K T V E I K S V S H V I E E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42207 361 41113 V84 V K L E A S T V E I E E R G V
Honey Bee Apis mellifera XP_395643 359 41055 S84 Q T V K L D A S T V E I E E R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788114 369 41790 T84 T V S I D A S T V E I E E R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32457 520 60021 G166 N D Q E E E E G Q G E G H E N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 47 N.A. 66.9 N.A. 98.6 98 N.A. 96.4 83.6 88.6 42.6 N.A. 66.4 67.3 N.A. 70.7
Protein Similarity: 100 64 N.A. 67.2 N.A. 99.1 98.6 N.A. 97.7 90 93 62.3 N.A. 79.5 78.9 N.A. 84.2
P-Site Identity: 100 53.3 N.A. 100 N.A. 100 100 N.A. 100 6.6 6.6 40 N.A. 6.6 73.3 N.A. 6.6
P-Site Similarity: 100 73.3 N.A. 100 N.A. 100 100 N.A. 100 20 20 73.3 N.A. 26.6 100 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 24 47 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 8 24 24 54 8 0 8 24 62 31 77 70 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 8 0 8 0 8 39 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % H
% Ile: 0 0 0 24 47 0 0 0 0 8 24 62 0 0 0 % I
% Lys: 16 8 0 8 0 8 0 0 8 0 0 0 8 0 0 % K
% Leu: 0 0 8 0 8 0 0 0 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 16 47 0 0 8 0 8 0 0 0 0 0 0 % Q
% Arg: 39 0 0 0 0 0 0 0 0 0 0 0 8 24 47 % R
% Ser: 0 0 8 0 0 8 31 54 8 0 0 0 0 0 0 % S
% Thr: 24 62 0 0 0 0 8 24 47 0 0 0 0 0 0 % T
% Val: 8 24 62 0 8 0 0 16 24 54 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _