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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT2
All Species:
22.73
Human Site:
Y105
Identified Species:
41.67
UniProt:
Q15019
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15019
NP_001008491.1
361
41487
Y105
T
V
V
D
T
P
G
Y
G
D
A
I
N
C
R
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
F114
T
I
V
D
T
P
G
F
G
D
A
V
D
N
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851909
532
59884
Y276
T
V
V
D
T
P
G
Y
G
D
A
I
N
C
R
Cat
Felis silvestris
Mouse
Mus musculus
P42208
361
41507
Y105
T
V
V
D
T
P
G
Y
G
D
A
I
N
C
R
Rat
Rattus norvegicus
Q91Y81
361
41574
Y105
T
V
V
D
T
P
G
Y
G
D
A
I
N
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513259
361
41490
Y105
T
V
V
D
T
P
G
Y
G
D
A
I
N
C
R
Chicken
Gallus gallus
Q5ZMH1
349
40206
G105
V
V
D
T
P
G
Y
G
D
A
I
N
S
Q
D
Frog
Xenopus laevis
Q63ZQ1
352
40432
G105
V
V
D
T
P
G
Y
G
D
A
M
N
C
V
D
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
F141
T
V
V
D
T
P
G
F
G
D
Q
I
N
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42207
361
41113
D105
V
D
T
P
G
F
G
D
A
I
D
N
S
N
S
Honey Bee
Apis mellifera
XP_395643
359
41055
Y105
T
V
V
D
T
P
G
Y
G
D
A
I
D
N
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788114
369
41790
G105
V
V
D
T
P
G
Y
G
D
A
I
N
N
N
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
Y187
H
K
V
K
I
K
S
Y
E
S
V
I
E
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47
N.A.
66.9
N.A.
98.6
98
N.A.
96.4
83.6
88.6
42.6
N.A.
66.4
67.3
N.A.
70.7
Protein Similarity:
100
64
N.A.
67.2
N.A.
99.1
98.6
N.A.
97.7
90
93
62.3
N.A.
79.5
78.9
N.A.
84.2
P-Site Identity:
100
60
N.A.
100
N.A.
100
93.3
N.A.
100
6.6
6.6
73.3
N.A.
6.6
80
N.A.
13.3
P-Site Similarity:
100
86.6
N.A.
100
N.A.
100
93.3
N.A.
100
13.3
6.6
80
N.A.
13.3
86.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
24
54
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
31
0
% C
% Asp:
0
8
24
62
0
0
0
8
24
62
8
0
16
0
31
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
8
0
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
24
70
24
62
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
8
16
62
0
0
0
% I
% Lys:
0
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
31
54
39
8
% N
% Pro:
0
0
0
8
24
62
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
39
% R
% Ser:
0
0
0
0
0
0
8
0
0
8
0
0
16
8
16
% S
% Thr:
62
0
8
24
62
0
0
0
0
0
0
0
0
0
8
% T
% Val:
31
77
70
0
0
0
0
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
24
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _