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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT2
All Species:
21.52
Human Site:
Y129
Identified Species:
39.44
UniProt:
Q15019
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15019
NP_001008491.1
361
41487
Y129
I
D
E
Q
F
E
R
Y
L
H
D
E
S
G
L
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
Y138
I
D
S
K
F
E
D
Y
L
N
A
E
S
R
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851909
532
59884
Y300
I
D
E
Q
F
E
R
Y
L
H
D
E
S
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P42208
361
41507
Y129
I
D
E
Q
F
E
R
Y
L
H
D
E
S
G
L
Rat
Rattus norvegicus
Q91Y81
361
41574
Y129
I
D
E
Q
F
E
R
Y
L
H
D
E
S
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513259
361
41490
Y129
I
D
E
Q
F
E
R
Y
L
H
D
E
S
G
L
Chicken
Gallus gallus
Q5ZMH1
349
40206
L129
D
N
Q
F
E
R
Y
L
H
D
E
S
G
L
N
Frog
Xenopus laevis
Q63ZQ1
352
40432
L129
D
N
Q
F
E
R
Y
L
H
D
E
S
G
L
N
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
F165
I
N
E
Q
Y
E
K
F
L
K
E
E
V
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42207
361
41113
R129
E
Q
Y
E
R
F
L
R
D
E
S
G
L
N
R
Honey Bee
Apis mellifera
XP_395643
359
41055
F129
I
D
D
Q
F
E
R
F
L
R
D
E
S
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788114
369
41790
L129
D
D
Q
Y
E
R
Y
L
N
D
E
S
G
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
F211
D
T
E
G
F
G
D
F
L
N
N
D
Q
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47
N.A.
66.9
N.A.
98.6
98
N.A.
96.4
83.6
88.6
42.6
N.A.
66.4
67.3
N.A.
70.7
Protein Similarity:
100
64
N.A.
67.2
N.A.
99.1
98.6
N.A.
97.7
90
93
62.3
N.A.
79.5
78.9
N.A.
84.2
P-Site Identity:
100
53.3
N.A.
100
N.A.
100
100
N.A.
100
0
0
40
N.A.
0
80
N.A.
6.6
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
100
N.A.
100
20
20
80
N.A.
6.6
93.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
62
8
0
0
0
16
0
8
24
47
8
0
0
0
% D
% Glu:
8
0
54
8
24
62
0
0
0
8
31
62
0
0
0
% E
% Phe:
0
0
0
16
62
8
0
24
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
0
8
24
47
0
% G
% His:
0
0
0
0
0
0
0
0
16
39
0
0
0
0
0
% H
% Ile:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
8
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
8
24
70
0
0
0
8
24
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
24
0
0
0
0
0
0
8
16
8
0
0
16
24
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
24
54
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
8
24
47
8
0
8
0
0
0
8
8
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
8
24
54
0
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
24
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _