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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT2
All Species:
35.45
Human Site:
Y211
Identified Species:
65
UniProt:
Q15019
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15019
NP_001008491.1
361
41487
Y211
E
E
H
N
I
K
I
Y
H
L
P
D
A
E
S
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
I217
K
E
I
Q
E
H
K
I
K
I
Y
E
F
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851909
532
59884
Y382
E
E
H
N
I
K
I
Y
H
L
P
D
A
E
S
Cat
Felis silvestris
Mouse
Mus musculus
P42208
361
41507
Y211
E
E
H
S
I
K
I
Y
H
L
P
D
A
E
S
Rat
Rattus norvegicus
Q91Y81
361
41574
Y211
E
E
H
S
I
K
I
Y
H
L
P
D
A
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513259
361
41490
Y211
E
E
H
C
I
K
I
Y
H
L
P
D
A
E
S
Chicken
Gallus gallus
Q5ZMH1
349
40206
Y210
S
E
H
G
I
R
I
Y
Q
L
P
D
A
D
S
Frog
Xenopus laevis
Q63ZQ1
352
40432
Y210
E
E
R
G
I
K
I
Y
H
L
P
D
A
E
S
Zebra Danio
Brachydanio rerio
A2BGU8
361
40623
E246
E
L
E
V
C
G
I
E
C
Y
P
Q
K
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42207
361
41113
Y209
E
S
H
G
I
K
I
Y
P
L
P
D
C
D
S
Honey Bee
Apis mellifera
XP_395643
359
41055
Y211
E
G
S
G
I
K
I
Y
P
L
P
D
C
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788114
369
41790
Y210
H
D
N
G
I
K
I
Y
H
M
S
D
S
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
L314
L
I
Q
S
N
I
E
L
F
K
P
P
I
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47
N.A.
66.9
N.A.
98.6
98
N.A.
96.4
83.6
88.6
42.6
N.A.
66.4
67.3
N.A.
70.7
Protein Similarity:
100
64
N.A.
67.2
N.A.
99.1
98.6
N.A.
97.7
90
93
62.3
N.A.
79.5
78.9
N.A.
84.2
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
66.6
86.6
26.6
N.A.
66.6
60
N.A.
46.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
93.3
80
86.6
26.6
N.A.
73.3
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
31.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% A
% Cys:
0
0
0
8
8
0
0
0
8
0
0
0
16
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
77
0
31
0
% D
% Glu:
70
62
8
0
8
0
8
8
0
0
0
8
0
54
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% F
% Gly:
0
8
0
39
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
54
0
0
8
0
0
54
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
77
8
85
8
0
8
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
70
8
0
8
8
0
0
8
0
0
% K
% Leu:
8
8
0
0
0
0
0
8
0
70
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
16
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
85
8
0
8
0
% P
% Gln:
0
0
8
8
0
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
8
24
0
0
0
0
0
0
8
0
8
0
85
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _