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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC7
All Species:
24.85
Human Site:
S183
Identified Species:
60.74
UniProt:
Q15024
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15024
NP_055819.2
291
31835
S183
G
S
K
D
I
E
L
S
D
D
P
Y
D
C
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533858
291
31908
S183
G
S
K
D
I
E
L
S
D
D
P
Y
D
C
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M0
291
31647
S183
G
A
K
D
I
E
L
S
D
D
P
Y
D
C
I
Rat
Rattus norvegicus
NP_001094195
291
31844
S183
G
S
K
D
I
E
L
S
D
D
P
Y
D
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086766
291
31926
S183
G
G
K
D
F
E
L
S
D
D
P
Y
D
C
V
Zebra Danio
Brachydanio rerio
NP_001017585
291
31936
S183
G
G
K
E
I
E
L
S
D
D
P
F
D
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725517
296
32369
S183
G
I
T
D
L
I
I
S
D
N
P
Y
D
C
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321194
287
30004
Q182
A
G
A
S
G
D
E
Q
P
E
V
D
I
S
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566318
286
29943
Q181
A
E
V
A
D
D
E
Q
P
E
I
D
I
S
D
Baker's Yeast
Sacchar. cerevisiae
Q05636
305
33943
R182
I
V
H
P
V
N
E
R
E
P
V
P
L
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.2
N.A.
93.1
95.8
N.A.
N.A.
N.A.
81.4
75.2
N.A.
48.9
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
98.6
N.A.
95.8
98.6
N.A.
N.A.
N.A.
92.7
90.3
N.A.
68.5
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
100
N.A.
N.A.
N.A.
80
73.3
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
100
100
N.A.
N.A.
N.A.
86.6
93.3
N.A.
73.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
36.7
N.A.
N.A.
38.1
21.9
N.A.
Protein Similarity:
58.7
N.A.
N.A.
59.1
40.6
N.A.
P-Site Identity:
0
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% C
% Asp:
0
0
0
60
10
20
0
0
70
60
0
20
70
0
20
% D
% Glu:
0
10
0
10
0
60
30
0
10
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
70
30
0
0
10
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
50
10
10
0
0
0
10
0
20
0
40
% I
% Lys:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
60
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
20
10
70
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
30
0
10
0
0
0
70
0
0
0
0
0
20
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
10
0
10
0
0
0
0
0
20
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _