Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOSC7 All Species: 21.82
Human Site: S251 Identified Species: 53.33
UniProt: Q15024 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15024 NP_055819.2 291 31835 S251 K G S L D P E S I F E M M E T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533858 291 31908 S251 K G S L D P E S I F E M M E T
Cat Felis silvestris
Mouse Mus musculus Q9D0M0 291 31647 S251 K G S L D P E S I F E M M E S
Rat Rattus norvegicus NP_001094195 291 31844 S251 K G S L D P E S I F E M M E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086766 291 31926 S251 K G S L D P E S I F E M I E T
Zebra Danio Brachydanio rerio NP_001017585 291 31936 S251 G G S L D P E S I F E M T E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725517 296 32369 H251 L T G G G A M H R D T M R N C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321194 287 30004 L250 S K R G S A G L D P S V I S D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_566318 286 29943 L249 T K R S G S G L D P S V I L D
Baker's Yeast Sacchar. cerevisiae Q05636 305 33943 K250 R E V V Q V S K A G G L P M D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.2 N.A. 93.1 95.8 N.A. N.A. N.A. 81.4 75.2 N.A. 48.9 N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 98.6 N.A. 95.8 98.6 N.A. N.A. N.A. 92.7 90.3 N.A. 68.5 N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 93.3 93.3 N.A. N.A. N.A. 93.3 80 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. N.A. 100 80 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: 36.7 N.A. N.A. 38.1 21.9 N.A.
Protein Similarity: 58.7 N.A. N.A. 59.1 40.6 N.A.
P-Site Identity: 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 20 0 0 10 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 60 0 0 0 20 10 0 0 0 0 30 % D
% Glu: 0 10 0 0 0 0 60 0 0 0 60 0 0 60 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 % F
% Gly: 10 60 10 20 20 0 20 0 0 10 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 60 0 0 0 30 0 0 % I
% Lys: 50 20 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 60 0 0 0 20 0 0 0 10 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 70 40 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 60 0 0 0 20 0 0 10 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 20 0 0 0 0 0 10 0 0 0 10 0 0 % R
% Ser: 10 0 60 10 10 10 10 60 0 0 20 0 0 10 20 % S
% Thr: 10 10 0 0 0 0 0 0 0 0 10 0 10 0 30 % T
% Val: 0 0 10 10 0 10 0 0 0 0 0 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _