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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EXOSC7 All Species: 26.36
Human Site: S43 Identified Species: 64.44
UniProt: Q15024 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15024 NP_055819.2 291 31835 S43 E V E T D V V S N T S G S A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533858 291 31908 S43 E V E T D V V S N T S G S A R
Cat Felis silvestris
Mouse Mus musculus Q9D0M0 291 31647 S43 E V E T D V V S N T S G S A R
Rat Rattus norvegicus NP_001094195 291 31844 S43 E V E T D V V S N T S G S A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001086766 291 31926 S43 E V E S D V V S N T T G S A R
Zebra Danio Brachydanio rerio NP_001017585 291 31936 S43 E I E T D V V S N T D G S A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725517 296 32369 S43 D L E T G L V S N A S G S A R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002321194 287 30004 P41 S I E T G V I P Q A N G S A R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_566318 286 29943 P40 Y V E T G V I P Q A N G S A R
Baker's Yeast Sacchar. cerevisiae Q05636 305 33943 K42 D V E I T F G K E F G D V S V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.2 N.A. 93.1 95.8 N.A. N.A. N.A. 81.4 75.2 N.A. 48.9 N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 98.6 N.A. 95.8 98.6 N.A. N.A. N.A. 92.7 90.3 N.A. 68.5 N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. N.A. 86.6 80 N.A. 66.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. N.A. N.A. 100 93.3 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: 36.7 N.A. N.A. 38.1 21.9 N.A.
Protein Similarity: 58.7 N.A. N.A. 59.1 40.6 N.A.
P-Site Identity: 46.6 N.A. N.A. 53.3 13.3 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 30 0 0 0 90 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 60 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 60 0 100 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 30 0 10 0 0 0 10 90 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 0 10 0 0 20 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % K
% Leu: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 70 0 20 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % R
% Ser: 10 0 0 10 0 0 0 70 0 0 50 0 90 10 0 % S
% Thr: 0 0 0 80 10 0 0 0 0 60 10 0 0 0 0 % T
% Val: 0 70 0 0 0 80 70 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _