KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC7
All Species:
19.7
Human Site:
Y110
Identified Species:
48.15
UniProt:
Q15024
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15024
NP_055819.2
291
31835
Y110
T
E
I
A
N
T
L
Y
R
I
F
N
N
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533858
291
31908
Y110
T
E
I
A
N
T
L
Y
R
I
F
N
N
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0M0
291
31647
T110
T
E
M
L
T
P
S
T
G
I
F
N
N
K
S
Rat
Rattus norvegicus
NP_001094195
291
31844
Y110
T
E
I
A
N
T
L
Y
R
I
F
N
N
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086766
291
31926
Y110
T
E
I
A
F
M
L
Y
K
I
F
D
N
R
S
Zebra Danio
Brachydanio rerio
NP_001017585
291
31936
Y110
V
E
L
S
N
T
L
Y
K
V
F
N
N
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725517
296
32369
Q110
Q
E
L
I
L
S
L
Q
N
A
Y
E
S
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321194
287
30004
Q108
A
E
L
S
V
A
L
Q
R
C
L
L
G
G
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566318
286
29943
Q107
S
E
L
A
L
A
L
Q
R
C
L
L
G
G
K
Baker's Yeast
Sacchar. cerevisiae
Q05636
305
33943
E109
V
L
C
S
R
I
I
E
K
S
V
R
R
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.2
N.A.
93.1
95.8
N.A.
N.A.
N.A.
81.4
75.2
N.A.
48.9
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
98.6
N.A.
95.8
98.6
N.A.
N.A.
N.A.
92.7
90.3
N.A.
68.5
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
53.3
100
N.A.
N.A.
N.A.
66.6
53.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
60
100
N.A.
N.A.
N.A.
86.6
86.6
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
36.7
N.A.
N.A.
38.1
21.9
N.A.
Protein Similarity:
58.7
N.A.
N.A.
59.1
40.6
N.A.
P-Site Identity:
20
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
50
0
20
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
20
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
90
0
0
0
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
60
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
20
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
40
10
0
10
10
0
0
50
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
30
0
0
0
0
40
20
% K
% Leu:
0
10
40
10
20
0
80
0
0
0
20
20
0
0
10
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
40
0
0
0
10
0
0
50
60
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
30
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
50
0
0
10
10
20
0
% R
% Ser:
10
0
0
30
0
10
10
0
0
10
0
0
10
10
50
% S
% Thr:
50
0
0
0
10
40
0
10
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
10
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _