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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LARS2 All Species: 16.06
Human Site: S718 Identified Species: 39.26
UniProt: Q15031 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15031 NP_056155.1 903 101976 S718 S P Q P Q L L S N K E K A E A
Chimpanzee Pan troglodytes XP_001147524 903 101984 S718 S P Q P Q L L S N K E K A E A
Rhesus Macaque Macaca mulatta XP_001114552 903 101790 S718 A P Q P Q L L S D K E K A E A
Dog Lupus familis XP_533856 903 101738 R718 V P R P E L L R N E E R A E S
Cat Felis silvestris
Mouse Mus musculus Q8VDC0 902 101462 N717 V P Q P Q L L N S K E K T K A
Rat Rattus norvegicus NP_001102257 714 79661 Q579 G A L S Q A S Q R L V L H S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513511 901 102576 S716 V P R P H Q L S N K E K A E V
Chicken Gallus gallus XP_418801 911 104405 S726 M P N P E V L S K K Q K A E A
Frog Xenopus laevis NP_001085563 900 101971 N715 V P N P H L L N K K E V A E A
Zebra Danio Brachydanio rerio NP_001099171 891 100485 N706 T P N P S I L N K R E R S E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96 90.4 N.A. 86.4 68.6 N.A. 79.6 70.3 69.4 64.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 97.9 95 N.A. 93 73.8 N.A. 88.9 82.1 81.4 78.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 53.3 N.A. 66.6 6.6 N.A. 66.6 60 60 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. 73.3 80 66.6 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 10 0 0 0 0 0 0 70 0 70 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 20 0 0 0 0 10 80 0 0 80 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 20 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 30 70 0 60 0 10 0 % K
% Leu: 0 0 10 0 0 60 90 0 0 10 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 30 0 0 0 0 30 40 0 0 0 0 0 0 % N
% Pro: 0 90 0 90 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 40 0 50 10 0 10 0 0 10 0 0 0 0 % Q
% Arg: 0 0 20 0 0 0 0 10 10 10 0 20 0 0 0 % R
% Ser: 20 0 0 10 10 0 10 50 10 0 0 0 10 10 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 40 0 0 0 0 10 0 0 0 0 10 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _