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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HERC3
All Species:
21.21
Human Site:
Y56
Identified Species:
51.85
UniProt:
Q15034
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15034
NP_055421.1
1050
117188
Y56
L
L
E
D
G
E
V
Y
T
C
G
L
N
T
K
Chimpanzee
Pan troglodytes
XP_517337
971
108923
S32
P
Q
V
C
G
F
I
S
D
R
S
V
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001100859
1050
117053
Y56
L
L
E
D
G
E
V
Y
T
C
G
L
N
T
K
Dog
Lupus familis
XP_535653
1051
117060
Y56
L
L
E
D
G
E
V
Y
T
C
G
L
N
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAV2
1057
118393
Y56
V
L
D
D
G
T
V
Y
T
C
G
C
N
D
L
Rat
Rattus norvegicus
Q5PQN1
1057
118521
Y56
V
L
D
D
G
T
V
Y
T
C
G
C
N
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508293
996
112121
L55
G
L
D
T
D
G
Q
L
G
L
P
G
T
E
E
Chicken
Gallus gallus
NP_001034387
1050
117242
Y56
L
L
E
D
G
E
V
Y
T
C
G
L
N
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.7
98.5
N.A.
55.5
55.5
N.A.
52.8
87.7
N.A.
22
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.3
99.9
99.5
N.A.
71.3
71.3
N.A.
68.6
94.3
N.A.
36.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
60
60
N.A.
6.6
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
73.3
73.3
N.A.
20
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
60
0
20
0
0
0
% C
% Asp:
0
0
30
60
10
0
0
0
10
0
0
0
0
20
0
% D
% Glu:
0
0
40
0
0
40
0
0
0
0
0
0
0
20
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
70
10
0
0
10
0
60
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
40
% K
% Leu:
40
70
0
0
0
0
0
10
0
10
0
40
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
60
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
20
0
0
60
0
0
0
10
40
0
% T
% Val:
20
0
10
0
0
0
60
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _