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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAM2
All Species:
17.58
Human Site:
S346
Identified Species:
42.96
UniProt:
Q15035
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15035
NP_036420.1
370
43328
S346
A
R
L
I
K
R
E
S
G
Y
H
E
N
G
V
Chimpanzee
Pan troglodytes
XP_518539
370
43295
S346
A
R
L
I
K
R
E
S
G
Y
H
E
N
G
V
Rhesus Macaque
Macaca mulatta
XP_001107590
373
43695
S349
A
R
L
I
K
R
E
S
G
Y
H
E
N
G
V
Dog
Lupus familis
XP_532171
606
69545
S582
A
R
L
I
K
R
E
S
G
Y
H
E
N
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q924Z5
370
43164
P346
A
K
L
L
K
R
E
P
G
Y
H
E
N
G
V
Rat
Rattus norvegicus
Q5XI41
374
43012
E351
R
S
S
R
K
G
T
E
N
G
V
N
G
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420046
376
43722
S352
V
K
P
L
K
R
D
S
G
Y
H
E
N
G
V
Frog
Xenopus laevis
Q6DED0
373
43081
E350
K
A
S
R
K
E
K
E
N
G
V
N
G
T
V
Zebra Danio
Brachydanio rerio
NP_998236
371
43641
V347
T
V
K
R
D
T
A
V
G
H
H
E
N
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178412
288
33476
W265
S
L
T
T
L
T
V
W
F
G
L
G
K
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
58.7
N.A.
90
52.6
N.A.
N.A.
70.4
52.8
65.7
N.A.
N.A.
N.A.
N.A.
40.5
Protein Similarity:
100
100
99.1
60
N.A.
94.5
70.8
N.A.
N.A.
79.5
69.4
78.9
N.A.
N.A.
N.A.
N.A.
55.1
P-Site Identity:
100
100
100
100
N.A.
80
13.3
N.A.
N.A.
66.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
N.A.
86.6
20
46.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
50
20
0
0
0
70
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
70
30
0
10
20
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
70
0
0
0
0
% H
% Ile:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
20
10
0
80
0
10
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
50
20
10
0
0
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
20
0
0
20
70
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
40
0
30
0
60
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
20
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
10
0
10
10
0
20
10
0
0
0
0
0
0
20
0
% T
% Val:
10
10
0
0
0
0
10
10
0
0
20
0
0
10
80
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _