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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KARS All Species: 20
Human Site: S590 Identified Species: 29.33
UniProt: Q15046 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15046 NP_005539.1 597 68048 S590 A T T D T L E S T T V G T S V
Chimpanzee Pan troglodytes XP_511115 611 69689 S604 A T T D T L E S T T V G T S V
Rhesus Macaque Macaca mulatta XP_001104312 647 73364 S640 A T T D T L E S T T V G T S V
Dog Lupus familis XP_536777 597 67971 S590 A T P E T L Q S T T A G T S V
Cat Felis silvestris
Mouse Mus musculus Q99MN1 595 67821 S588 A T T E T P E S T E A S P S V
Rat Rattus norvegicus NP_001006968 626 71605 S619 T A T E T P E S T E A S P S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508683 601 68342 D594 A N P S S S E D T G P G T S V
Chicken Gallus gallus NP_001025754 590 67899 Q583 K K E G H L E Q P A E G T S V
Frog Xenopus laevis NP_001080633 605 69680
Zebra Danio Brachydanio rerio NP_001002386 602 69106 A595 P E D N K P A A P A E G T S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572573 574 64642 A566 E D A N R T A A E T A P T A Q
Honey Bee Apis mellifera XP_623936 611 70543 N603 S E D D K T L N D K I N H V E
Nematode Worm Caenorhab. elegans Q22099 572 65118
Sea Urchin Strong. purpuratus XP_793463 584 66865 T577 G Q P E E G A T E T L I K S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPI1 626 70869 A619 E E S A A A Q A P L T E E K K
Baker's Yeast Sacchar. cerevisiae P15180 591 67940
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 89.4 94.3 N.A. 92.6 86.9 N.A. 86.6 82.9 76 76.9 N.A. 68.1 64.9 58.9 63.8
Protein Similarity: 100 97.7 91.8 97.8 N.A. 96.4 91.5 N.A. 92.6 89.1 85.1 87.2 N.A. 79.9 78.8 75.2 78.3
P-Site Identity: 100 100 100 73.3 N.A. 60 46.6 N.A. 46.6 40 0 26.6 N.A. 13.3 6.6 0 13.3
P-Site Similarity: 100 100 100 86.6 N.A. 66.6 53.3 N.A. 53.3 40 0 40 N.A. 33.3 26.6 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. 53.9 54.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.9 70.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 7 7 7 7 7 19 19 0 13 25 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 13 25 0 0 0 7 7 0 0 0 0 0 0 % D
% Glu: 13 19 7 25 7 0 44 0 13 13 13 7 7 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 0 7 0 0 0 7 0 44 0 0 0 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % I
% Lys: 7 7 0 0 13 0 0 0 0 7 0 0 7 7 7 % K
% Leu: 0 0 0 0 0 32 7 0 0 7 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 13 0 0 0 7 0 0 0 7 0 0 0 % N
% Pro: 7 0 19 0 0 19 0 0 19 0 7 7 13 0 0 % P
% Gln: 0 7 0 0 0 0 13 7 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 0 7 7 7 7 0 38 0 0 0 13 0 63 7 % S
% Thr: 7 32 32 0 38 13 0 7 44 38 7 0 50 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 19 0 0 7 57 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _