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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KARS All Species: 46.06
Human Site: T366 Identified Species: 67.56
UniProt: Q15046 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15046 NP_005539.1 597 68048 T366 S G M V K H I T G S Y K V T Y
Chimpanzee Pan troglodytes XP_511115 611 69689 T380 S G M V K H I T G S Y K V T Y
Rhesus Macaque Macaca mulatta XP_001104312 647 73364 T416 S G M V K H I T G S Y K I T Y
Dog Lupus familis XP_536777 597 67971 T366 S G M V K H I T G S Y K V T Y
Cat Felis silvestris
Mouse Mus musculus Q99MN1 595 67821 T364 S G M V K S I T G S Y K I T Y
Rat Rattus norvegicus NP_001006968 626 71605 T395 S G M V R S I T G S Y K I T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508683 601 68342 R370 S G M V K H I R G S Y K I A Y
Chicken Gallus gallus NP_001025754 590 67899 T363 S G M V K H I T G S Y K I T Y
Frog Xenopus laevis NP_001080633 605 69680 T378 S G M V K H I T G G Y K V P Y
Zebra Danio Brachydanio rerio NP_001002386 602 69106 T379 S G M V K H I T G A Y K V T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572573 574 64642 R349 S G M V K A I R G S Y K V I Y
Honey Bee Apis mellifera XP_623936 611 70543 H377 S G M I K S I H G S Y K I T Y
Nematode Worm Caenorhab. elegans Q22099 572 65118 K345 S S M V M S I K G T Y K I E Y
Sea Urchin Strong. purpuratus XP_793463 584 66865 T353 S G M V K F V T G S T K V T Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPI1 626 70869 T402 S G M V K E L T G G Y K I K Y
Baker's Yeast Sacchar. cerevisiae P15180 591 67940 T369 S E M V K E I T G S Y I I K Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 89.4 94.3 N.A. 92.6 86.9 N.A. 86.6 82.9 76 76.9 N.A. 68.1 64.9 58.9 63.8
Protein Similarity: 100 97.7 91.8 97.8 N.A. 96.4 91.5 N.A. 92.6 89.1 85.1 87.2 N.A. 79.9 78.8 75.2 78.3
P-Site Identity: 100 100 93.3 100 N.A. 86.6 80 N.A. 80 93.3 86.6 93.3 N.A. 80 73.3 53.3 80
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 100 86.6 100 N.A. 80 86.6 66.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 53.9 54.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.9 70.8 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 0 0 7 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 0 0 0 13 0 0 0 0 0 0 0 7 0 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 88 0 0 0 0 0 0 100 13 0 0 0 0 0 % G
% His: 0 0 0 0 0 50 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 88 0 0 0 0 7 57 7 0 % I
% Lys: 0 0 0 0 88 0 0 7 0 0 0 94 0 13 0 % K
% Leu: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % L
% Met: 0 0 100 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 0 0 13 0 0 0 0 0 0 0 % R
% Ser: 100 7 0 0 0 25 0 0 0 75 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 75 0 7 7 0 0 63 0 % T
% Val: 0 0 0 94 0 0 7 0 0 0 0 0 44 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 94 0 0 0 100 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _