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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KARS All Species: 46.36
Human Site: Y145 Identified Species: 68
UniProt: Q15046 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15046 NP_005539.1 597 68048 Y145 S G G K L I F Y D L R G E G V
Chimpanzee Pan troglodytes XP_511115 611 69689 Y159 S G G K L I F Y D L R G E G V
Rhesus Macaque Macaca mulatta XP_001104312 647 73364 Y195 S G G K L I F Y D L R G E G V
Dog Lupus familis XP_536777 597 67971 Y145 S G G K L I F Y D L R G E G V
Cat Felis silvestris
Mouse Mus musculus Q99MN1 595 67821 Y143 S G G K L I F Y D L R G E G V
Rat Rattus norvegicus NP_001006968 626 71605 Y174 S G G K L I F Y D L R G E G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508683 601 68342 Y149 S G G K L I F Y D L R G E G V
Chicken Gallus gallus NP_001025754 590 67899 Y142 S G G K L I F Y D L R G E G V
Frog Xenopus laevis NP_001080633 605 69680 D158 G A K L I F Y D L R G E G T K
Zebra Danio Brachydanio rerio NP_001002386 602 69106 Y158 S G A K L L F Y D L R G E G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572573 574 64642 V137 L R G E G V K V Q V M A S A K
Honey Bee Apis mellifera XP_623936 611 70543 F156 S G A K L I F F D L R G E G V
Nematode Worm Caenorhab. elegans Q22099 572 65118 I133 I H G E G T H I Q I M A N A K
Sea Urchin Strong. purpuratus XP_793463 584 66865 Y132 S G A K L I F Y D L R G E G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZPI1 626 70869 Y159 S S S K L F F Y D L H G D D F
Baker's Yeast Sacchar. cerevisiae P15180 591 67940 Y143 S G S K L K F Y V L H G D G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.5 89.4 94.3 N.A. 92.6 86.9 N.A. 86.6 82.9 76 76.9 N.A. 68.1 64.9 58.9 63.8
Protein Similarity: 100 97.7 91.8 97.8 N.A. 96.4 91.5 N.A. 92.6 89.1 85.1 87.2 N.A. 79.9 78.8 75.2 78.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 0 86.6 N.A. 6.6 86.6 6.6 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 93.3 N.A. 26.6 93.3 20 93.3
Percent
Protein Identity: N.A. N.A. N.A. 53.9 54.7 N.A.
Protein Similarity: N.A. N.A. N.A. 69.9 70.8 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 19 0 0 0 0 0 0 0 0 13 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 75 0 0 0 13 7 0 % D
% Glu: 0 0 0 13 0 0 0 0 0 0 0 7 69 0 0 % E
% Phe: 0 0 0 0 0 13 82 7 0 0 0 0 0 0 7 % F
% Gly: 7 75 63 0 13 0 0 0 0 0 7 82 7 75 0 % G
% His: 0 7 0 0 0 0 7 0 0 0 13 0 0 0 0 % H
% Ile: 7 0 0 0 7 63 0 7 0 7 0 0 0 0 0 % I
% Lys: 0 0 7 82 0 7 7 0 0 0 0 0 0 0 19 % K
% Leu: 7 0 0 7 82 7 0 0 7 82 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 7 69 0 0 0 0 % R
% Ser: 82 7 13 0 0 0 0 0 0 0 0 0 7 0 0 % S
% Thr: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % T
% Val: 0 0 0 0 0 7 0 7 7 7 0 0 0 0 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _