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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC14
All Species:
21.21
Human Site:
Y257
Identified Species:
51.85
UniProt:
Q15048
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15048
NP_055480.1
493
54513
Y257
L
A
S
L
R
L
H
Y
V
H
G
D
S
R
Q
Chimpanzee
Pan troglodytes
XP_517600
514
56800
D252
T
L
P
T
K
A
F
D
A
P
P
T
Y
A
S
Rhesus Macaque
Macaca mulatta
XP_001094307
493
54555
Y257
L
A
S
L
R
L
H
Y
V
H
G
D
S
R
Q
Dog
Lupus familis
XP_539223
552
61120
Y316
L
A
S
L
R
L
H
Y
V
H
G
D
S
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC16
493
54950
Y257
L
A
S
L
R
L
H
Y
V
H
G
D
S
R
Q
Rat
Rattus norvegicus
Q569B5
493
54896
Y257
L
A
S
L
R
L
H
Y
V
H
G
D
S
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513278
516
57697
A254
L
V
S
L
T
L
P
A
R
T
F
D
V
H
R
Chicken
Gallus gallus
XP_426030
516
58719
A254
L
M
S
L
T
L
P
A
R
T
F
N
V
R
R
Frog
Xenopus laevis
Q640Z9
509
57042
Y273
L
Q
S
L
K
L
P
Y
S
N
V
D
V
R
R
Zebra Danio
Brachydanio rerio
Q1L8H0
526
59513
A254
L
R
S
L
T
F
P
A
Q
A
L
N
V
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.8
98.7
86
N.A.
94.1
92.6
N.A.
28.6
28.4
47.3
28.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
50.5
99.1
87.1
N.A.
96.1
95.5
N.A.
48.4
47.4
64.8
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
33.3
33.3
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
40
46.6
66.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
10
0
30
10
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
70
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
20
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% G
% His:
0
0
0
0
0
0
50
0
0
50
0
0
0
20
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
90
10
0
90
0
80
0
0
0
0
10
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
20
0
0
0
% N
% Pro:
0
0
10
0
0
0
40
0
0
10
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
50
% Q
% Arg:
0
10
0
0
50
0
0
0
20
0
0
0
0
70
40
% R
% Ser:
0
0
90
0
0
0
0
0
10
0
0
0
50
0
10
% S
% Thr:
10
0
0
10
30
0
0
0
0
20
0
10
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
50
0
10
0
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _