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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRD3 All Species: 34.85
Human Site: S261 Identified Species: 76.67
UniProt: Q15059 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15059 NP_031397.1 726 79542 S261 S A I T A S R S E S P P P L S
Chimpanzee Pan troglodytes XP_001170299 726 79569 S261 S A I T A S R S E S P P P L S
Rhesus Macaque Macaca mulatta XP_001099107 726 79563 S261 S A I T A S R S E S P P P L S
Dog Lupus familis XP_858138 716 78567 S249 S A I T A S R S E S P P P L S
Cat Felis silvestris
Mouse Mus musculus Q8K2F0 726 79743 S260 S A I T A S R S E S P P P L S
Rat Rattus norvegicus Q6MGA9 798 88032 S297 T A I L A P G S P A S P P G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505872 1284 139915 S817 S A I T A S R S E S P T P L T
Chicken Gallus gallus XP_425330 722 79727 S257 S V I T A S R S E S P T P L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116861 683 74548 S245 S A I T A S R S Q S P T P I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13709 2038 205327 T417 N A F E S P Y T Q M D S K S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35817 686 76959 A271 A K G R R S S A Q E D A P I V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99 93.6 N.A. 95.5 60.6 N.A. 52.8 91.5 N.A. 69.2 N.A. 21.8 N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.3 96.5 N.A. 97.3 70.1 N.A. 54.5 94.2 N.A. 76.1 N.A. 27.6 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 46.6 N.A. 86.6 86.6 N.A. 73.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 93.3 86.6 N.A. 86.6 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 82 0 0 82 0 0 10 0 10 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 64 10 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 82 0 0 0 0 0 0 0 0 0 0 19 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 0 0 0 0 0 64 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 19 0 0 10 0 73 55 91 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 0 73 0 0 0 0 0 0 0 0 % R
% Ser: 73 0 0 0 10 82 10 82 0 73 10 10 0 10 64 % S
% Thr: 10 0 0 73 0 0 0 10 0 0 0 28 0 0 10 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _