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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX1
All Species:
38.79
Human Site:
T222
Identified Species:
65.64
UniProt:
Q15067
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15067
NP_004026.2
660
74424
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Chimpanzee
Pan troglodytes
XP_001149084
660
74412
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Dog
Lupus familis
XP_540441
661
75017
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0H0
661
74616
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Rat
Rattus norvegicus
P07872
661
74660
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
T194
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Chicken
Gallus gallus
NP_001006205
662
74462
T223
H
E
P
L
P
G
I
T
V
G
D
I
G
P
K
Frog
Xenopus laevis
NP_001084389
661
74039
V222
H
E
P
L
P
G
V
V
V
G
D
I
G
P
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
D235
H
R
P
M
P
G
I
D
I
G
D
I
G
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
R234
Y
S
V
M
S
G
V
R
V
G
D
I
G
T
K
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
E243
H
L
P
H
P
G
V
E
L
G
D
I
G
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
T221
H
S
P
L
P
N
I
T
V
G
D
I
G
T
K
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
S272
F
Q
L
L
A
G
V
S
I
G
D
I
G
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
89.2
N.A.
87.4
88.5
N.A.
75.7
77
71.7
N.A.
N.A.
44.2
N.A.
38.6
48.5
Protein Similarity:
100
99.8
99
94
N.A.
94
93.9
N.A.
85.3
87.4
83.9
N.A.
N.A.
63.5
N.A.
59.2
64.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
80
N.A.
N.A.
66.6
N.A.
46.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
N.A.
N.A.
86.6
N.A.
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.2
29.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.5
49.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
100
0
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
93
0
0
0
100
0
0
100
0
0
% G
% His:
86
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
72
0
15
0
0
100
0
0
0
% I
% Lys:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
100
% K
% Leu:
0
8
8
79
0
0
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
86
0
86
0
0
0
0
0
0
0
0
72
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
0
8
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
65
0
0
0
0
0
22
0
% T
% Val:
0
0
8
0
0
0
29
8
79
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _