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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACOX1
All Species:
38.48
Human Site:
Y352
Identified Species:
65.13
UniProt:
Q15067
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15067
NP_004026.2
660
74424
Y352
G
A
Y
M
K
E
T
Y
H
R
I
N
E
G
I
Chimpanzee
Pan troglodytes
XP_001149084
660
74412
Y352
G
A
Y
M
K
E
T
Y
H
R
I
N
E
G
I
Rhesus Macaque
Macaca mulatta
XP_001102134
660
74475
Y352
G
A
Y
M
K
E
T
Y
H
R
I
N
E
G
I
Dog
Lupus familis
XP_540441
661
75017
Y352
G
A
Y
M
K
E
T
Y
H
R
I
N
E
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0H0
661
74616
Y352
G
R
Y
I
K
E
T
Y
M
R
I
N
E
S
I
Rat
Rattus norvegicus
P07872
661
74660
Y352
G
R
Y
M
K
E
T
Y
L
R
I
N
E
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514051
633
70993
Y324
G
A
F
M
K
E
T
Y
H
R
I
N
V
D
I
Chicken
Gallus gallus
NP_001006205
662
74462
Y353
G
A
Y
I
K
D
T
Y
H
R
I
S
G
D
I
Frog
Xenopus laevis
NP_001084389
661
74039
Y352
G
S
Y
M
S
H
T
Y
H
R
I
S
A
E
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KML2
669
74269
Y365
G
D
G
I
W
N
M
Y
N
V
I
S
G
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34355
659
74696
R361
N
T
A
A
A
T
V
R
Q
M
T
E
N
C
I
Sea Urchin
Strong. purpuratus
XP_783450
682
76709
Y373
G
R
E
M
M
K
H
Y
F
E
S
L
A
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65202
664
74283
Y355
G
E
W
L
K
W
L
Y
T
D
V
T
E
R
L
Baker's Yeast
Sacchar. cerevisiae
P13711
748
84024
S419
L
D
E
L
Y
N
A
S
S
S
A
Y
K
A
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
89.2
N.A.
87.4
88.5
N.A.
75.7
77
71.7
N.A.
N.A.
44.2
N.A.
38.6
48.5
Protein Similarity:
100
99.8
99
94
N.A.
94
93.9
N.A.
85.3
87.4
83.9
N.A.
N.A.
63.5
N.A.
59.2
64.9
P-Site Identity:
100
100
100
93.3
N.A.
73.3
80
N.A.
80
66.6
60
N.A.
N.A.
26.6
N.A.
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
86.6
86.6
73.3
N.A.
N.A.
46.6
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.2
29.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.5
49.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
8
8
8
0
8
0
0
0
8
0
15
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
15
0
0
0
8
0
0
0
8
0
0
0
22
0
% D
% Glu:
0
8
15
0
0
50
0
0
0
8
0
8
50
22
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
86
0
8
0
0
0
0
0
0
0
0
0
15
22
0
% G
% His:
0
0
0
0
0
8
8
0
50
0
0
0
0
0
0
% H
% Ile:
0
0
0
22
0
0
0
0
0
0
72
0
0
0
79
% I
% Lys:
0
0
0
0
65
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
0
0
15
0
0
8
0
8
0
0
8
0
0
8
% L
% Met:
0
0
0
58
8
0
8
0
8
8
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
15
0
0
8
0
0
50
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
22
0
0
0
0
0
8
0
65
0
0
0
8
0
% R
% Ser:
0
8
0
0
8
0
0
8
8
8
8
22
0
15
0
% S
% Thr:
0
8
0
0
0
8
65
0
8
0
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
8
0
8
0
0
% V
% Trp:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
58
0
8
0
0
86
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _