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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RY6
All Species:
28.18
Human Site:
S291
Identified Species:
68.89
UniProt:
Q15077
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15077
NP_004145.1
328
36429
S291
K
G
T
R
P
F
A
S
A
N
S
V
L
D
P
Chimpanzee
Pan troglodytes
XP_508629
328
36394
S291
K
G
T
R
P
F
A
S
A
N
S
V
L
D
P
Rhesus Macaque
Macaca mulatta
XP_001115246
328
36493
S291
K
G
T
R
P
F
A
S
A
N
S
V
L
D
P
Dog
Lupus familis
XP_542320
325
36047
A281
P
V
L
E
A
F
A
A
A
Y
K
G
T
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK9
328
36703
S291
K
G
T
R
P
F
A
S
V
N
S
V
L
D
P
Rat
Rattus norvegicus
Q63371
328
36659
S291
K
G
T
R
P
F
A
S
A
N
S
V
L
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512819
362
41537
S301
K
I
W
R
P
L
V
S
L
N
S
C
F
N
P
Chicken
Gallus gallus
Q98907
328
37568
S286
K
C
T
R
P
F
A
S
M
N
S
V
L
D
P
Frog
Xenopus laevis
P79928
537
62006
A308
V
T
R
P
L
A
S
A
N
S
C
I
D
P
I
Zebra Danio
Brachydanio rerio
XP_694459
317
36513
S279
K
S
T
R
P
F
A
S
M
N
S
V
L
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.5
93.2
N.A.
86.5
87.5
N.A.
37.5
62.5
26.6
59.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.4
95.1
N.A.
90.8
91.4
N.A.
51.6
73.4
36.3
71.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
93.3
100
N.A.
46.6
86.6
0
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
100
N.A.
53.3
86.6
26.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
80
20
50
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
70
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
80
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
80
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
10
0
10
10
0
0
10
0
0
0
70
0
0
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
80
0
0
0
10
0
% N
% Pro:
10
0
0
10
80
0
0
0
0
0
0
0
0
10
90
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
80
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
0
0
0
0
10
80
0
10
80
0
0
0
0
% S
% Thr:
0
10
70
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
10
10
0
0
0
0
10
0
10
0
0
70
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _