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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5R1
All Species:
21.52
Human Site:
S214
Identified Species:
43.03
UniProt:
Q15078
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15078
NP_003876.1
307
34060
S214
L
C
R
D
V
I
S
S
E
V
G
S
D
H
E
Chimpanzee
Pan troglodytes
XP_001158783
424
45536
S331
L
C
R
D
V
I
S
S
E
V
G
S
D
H
E
Rhesus Macaque
Macaca mulatta
XP_001113074
307
34072
S214
L
C
R
D
V
I
S
S
E
V
G
S
D
H
E
Dog
Lupus familis
XP_548274
307
34112
S214
L
C
R
D
V
I
S
S
E
V
G
S
D
H
E
Cat
Felis silvestris
Mouse
Mus musculus
O35926
369
38896
D250
C
R
E
S
L
S
G
D
E
L
A
S
A
A
E
Rat
Rattus norvegicus
P61810
307
34013
S214
L
C
R
D
V
I
S
S
E
V
G
S
D
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510972
134
15408
E48
P
E
L
A
A
D
H
E
L
Q
A
V
L
L
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079141
293
32627
T207
I
D
G
D
S
V
A
T
E
H
D
L
Q
A
T
Zebra Danio
Brachydanio rerio
NP_001002515
310
34763
T214
V
V
S
S
E
V
A
T
E
H
E
L
Q
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523535
472
53508
G380
L
V
R
E
L
V
S
G
E
E
S
K
E
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22695
356
39856
D222
I
F
I
S
N
N
C
D
V
S
D
F
D
P
A
Sea Urchin
Strong. purpuratus
XP_794538
375
41683
L229
L
Q
C
S
T
S
E
L
L
K
C
L
G
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.6
99
N.A.
48.5
98.3
N.A.
36.4
N.A.
66.1
79.6
N.A.
35.5
N.A.
35.1
42.1
Protein Similarity:
100
70
99.6
99.6
N.A.
57.9
99
N.A.
40.7
N.A.
79.8
88
N.A.
46.4
N.A.
50.5
57.3
P-Site Identity:
100
100
100
100
N.A.
20
100
N.A.
0
N.A.
13.3
6.6
N.A.
26.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
0
N.A.
40
33.3
N.A.
60
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
17
0
0
0
17
0
9
25
9
% A
% Cys:
9
42
9
0
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
50
0
9
0
17
0
0
17
0
50
0
9
% D
% Glu:
0
9
9
9
9
0
9
9
75
9
9
0
9
0
50
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
0
0
9
0
0
0
9
9
0
0
42
0
9
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
17
0
0
0
42
0
% H
% Ile:
17
0
9
0
0
42
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% K
% Leu:
59
0
9
0
17
0
0
9
17
9
0
25
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
9
0
0
0
0
0
0
0
9
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
0
0
17
0
0
% Q
% Arg:
0
9
50
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
34
9
17
50
42
0
9
9
50
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
17
0
0
0
0
0
0
17
% T
% Val:
9
17
0
0
42
25
0
0
9
42
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _