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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
9.09
Human Site:
S106
Identified Species:
12.5
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S106
P
T
I
K
I
F
G
S
N
K
N
R
P
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S190
P
T
I
K
I
F
G
S
N
K
N
R
P
E
D
Dog
Lupus familis
XP_532876
440
48280
S106
P
T
I
K
I
F
G
S
N
K
N
R
P
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
A106
P
T
I
K
I
F
G
A
N
K
N
K
P
E
D
Rat
Rattus norvegicus
Q63081
440
48155
A106
P
T
I
K
I
F
G
A
N
K
N
K
P
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
A102
G
E
A
I
V
D
A
A
L
S
A
L
R
P
L
Chicken
Gallus gallus
Q8JG64
505
56163
D106
P
T
L
K
I
F
R
D
G
E
E
S
G
T
Y
Frog
Xenopus laevis
NP_001086643
442
47765
A106
P
T
I
K
V
F
G
A
N
K
N
K
P
D
D
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
G106
P
T
I
K
I
F
G
G
N
K
H
K
P
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A146
D
L
T
S
V
A
D
A
E
Q
F
L
K
D
N
Honey Bee
Apis mellifera
XP_395981
427
47177
I102
P
T
I
K
I
F
G
I
D
N
K
P
E
D
Y
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
A105
P
T
L
K
I
F
G
A
D
K
K
K
P
T
D
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
F94
A
P
Y
N
V
R
G
F
P
T
I
K
V
F
G
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
R99
P
V
D
Y
Q
G
A
R
D
V
K
P
I
A
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
K56
A
P
W
C
G
H
C
K
K
L
A
P
E
Y
E
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
G12
N
I
I
K
L
L
L
G
L
F
I
M
N
E
V
Red Bread Mold
Neurospora crassa
Q92249
369
39263
L63
L
A
P
V
Y
E
E
L
A
T
A
L
E
Y
A
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
86.6
N.A.
0
33.3
73.3
80
N.A.
0
46.6
60
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
46.6
100
93.3
N.A.
33.3
60
86.6
20
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
0
20
0
P-Site Similarity:
20
N.A.
N.A.
6.6
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
6
6
0
0
6
12
36
6
0
18
0
0
6
6
% A
% Cys:
0
0
0
6
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
6
0
0
6
6
6
18
0
0
0
0
18
48
% D
% Glu:
0
6
0
0
0
6
6
0
6
6
6
0
18
42
12
% E
% Phe:
0
0
0
0
0
59
0
6
0
6
6
0
0
6
0
% F
% Gly:
6
0
0
0
6
6
59
12
6
0
0
0
6
0
6
% G
% His:
0
0
0
0
0
6
0
0
0
0
6
0
0
0
0
% H
% Ile:
0
6
53
6
53
0
0
6
0
0
12
0
6
0
0
% I
% Lys:
0
0
0
65
0
0
0
6
6
48
18
36
6
0
0
% K
% Leu:
6
6
12
0
6
6
6
6
12
6
0
18
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
6
0
0
6
0
0
0
0
42
6
36
0
6
0
6
% N
% Pro:
65
12
6
0
0
0
0
0
6
0
0
18
48
6
0
% P
% Gln:
0
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
6
6
6
0
0
0
18
6
0
0
% R
% Ser:
0
0
0
6
0
0
0
18
0
6
0
6
0
0
0
% S
% Thr:
0
59
6
0
0
0
0
0
0
12
0
0
0
12
0
% T
% Val:
0
6
0
6
24
0
0
0
0
6
0
0
6
0
6
% V
% Trp:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
6
6
0
0
0
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _