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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
25.76
Human Site:
S143
Identified Species:
35.42
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S143
K
D
R
L
G
G
R
S
G
G
Y
S
S
G
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S227
K
D
R
L
G
G
R
S
G
G
Y
S
S
G
K
Dog
Lupus familis
XP_532876
440
48280
G143
K
D
R
L
G
G
R
G
G
G
Y
S
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S143
K
D
R
L
G
G
R
S
G
G
Y
S
S
G
K
Rat
Rattus norvegicus
Q63081
440
48155
S143
K
D
R
L
G
G
R
S
G
G
Y
S
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
E139
S
S
K
K
D
V
I
E
L
T
D
D
N
F
D
Chicken
Gallus gallus
Q8JG64
505
56163
F143
A
L
S
S
V
A
D
F
E
K
F
I
G
D
K
Frog
Xenopus laevis
NP_001086643
442
47765
S143
K
D
R
L
G
G
R
S
G
G
S
D
S
G
R
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
T143
K
D
R
L
G
G
K
T
G
G
S
D
Y
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
V183
A
N
A
L
D
S
F
V
F
G
V
S
S
N
A
Honey Bee
Apis mellifera
XP_395981
427
47177
S139
K
I
L
G
G
K
R
S
T
G
D
F
K
S
K
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
S142
S
A
R
L
G
G
K
S
S
G
S
S
S
S
G
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
V131
L
K
T
V
K
D
M
V
N
A
R
S
S
G
G
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
L136
S
E
K
S
E
T
S
L
S
V
E
L
N
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
G93
K
S
V
C
T
K
Y
G
V
S
G
Y
P
T
I
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
T49
A
I
H
N
T
N
Y
T
S
L
V
E
F
Y
A
Red Bread Mold
Neurospora crassa
Q92249
369
39263
K100
V
Q
G
F
P
T
L
K
F
F
D
G
K
S
E
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
0
6.6
80
53.3
N.A.
26.6
40
53.3
20
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
13.3
13.3
86.6
73.3
N.A.
33.3
40
60
26.6
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
6.6
0
0
P-Site Similarity:
26.6
N.A.
N.A.
6.6
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
6
6
0
0
6
0
0
0
6
0
0
0
0
12
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
0
12
6
6
0
0
0
18
18
0
6
6
% D
% Glu:
0
6
0
0
6
0
0
6
6
0
6
6
0
0
6
% E
% Phe:
0
0
0
6
0
0
6
6
12
6
6
6
6
6
0
% F
% Gly:
0
0
6
6
53
48
0
12
42
59
6
6
6
42
12
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
6
0
0
0
0
6
0
0
6
% I
% Lys:
53
6
12
6
6
12
12
6
0
6
0
0
12
0
42
% K
% Leu:
6
6
6
53
0
0
6
6
6
6
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
6
0
6
0
0
6
0
0
0
12
6
0
% N
% Pro:
0
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% P
% Gln:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
48
0
0
0
42
0
0
0
6
0
0
0
18
% R
% Ser:
18
12
6
12
0
6
6
42
18
6
18
48
53
30
0
% S
% Thr:
0
0
6
0
12
12
0
12
6
6
0
0
0
6
0
% T
% Val:
6
0
6
6
6
6
0
12
6
6
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
30
6
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _