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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
13.03
Human Site:
S158
Identified Species:
17.92
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S158
Q
G
R
S
D
S
S
S
K
K
D
V
I
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S242
Q
G
R
S
D
S
S
S
K
K
D
V
I
E
L
Dog
Lupus familis
XP_532876
440
48280
N158
Q
G
R
S
E
S
S
N
K
K
D
V
I
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S158
Q
G
R
G
D
S
S
S
K
K
D
V
V
E
L
Rat
Rattus norvegicus
Q63081
440
48155
S158
Q
G
R
G
D
S
S
S
K
K
D
V
V
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
D154
K
N
V
L
E
S
D
D
V
W
L
V
E
F
Y
Chicken
Gallus gallus
Q8JG64
505
56163
F158
D
A
S
V
V
G
F
F
R
D
A
S
G
D
A
Frog
Xenopus laevis
NP_001086643
442
47765
G158
Q
S
H
S
G
G
S
G
G
S
K
K
D
V
I
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
N158
Q
S
G
G
G
A
G
N
K
K
D
V
V
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
A198
D
V
I
A
K
Y
E
A
K
D
N
G
V
V
L
Honey Bee
Apis mellifera
XP_395981
427
47177
L154
D
S
K
D
V
I
E
L
T
D
D
T
F
D
N
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
R157
S
G
S
G
S
G
K
R
G
G
G
G
S
G
N
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
G146
G
G
G
G
R
G
S
G
G
S
G
S
G
G
S
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
K151
N
F
D
E
L
V
L
K
S
K
E
L
W
I
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
L108
Q
W
F
P
K
G
S
L
E
P
Q
K
Y
E
G
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
K64
P
W
C
G
H
C
K
K
L
S
S
T
F
R
K
Red Bread Mold
Neurospora crassa
Q92249
369
39263
G115
Q
P
V
D
Y
K
G
G
R
D
L
D
S
L
S
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
86.6
N.A.
13.3
0
20
46.6
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
26.6
13.3
26.6
66.6
N.A.
40
20
6.6
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
20
0
6.6
P-Site Similarity:
26.6
N.A.
N.A.
26.6
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
0
6
0
6
0
0
6
0
0
0
6
% A
% Cys:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
0
6
12
24
0
6
6
0
24
42
6
6
12
0
% D
% Glu:
0
0
0
6
12
0
12
0
6
0
6
0
6
42
0
% E
% Phe:
0
6
6
0
0
0
6
6
0
0
0
0
12
6
0
% F
% Gly:
6
42
12
36
12
30
12
18
18
6
12
12
12
12
6
% G
% His:
0
0
6
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
0
6
0
0
0
0
0
0
18
6
6
% I
% Lys:
6
0
6
0
12
6
12
12
42
42
6
12
0
0
6
% K
% Leu:
0
0
0
6
6
0
6
12
6
0
12
6
0
6
42
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
0
0
0
0
0
12
0
0
6
0
0
0
12
% N
% Pro:
6
6
0
6
0
0
0
0
0
6
0
0
0
0
0
% P
% Gln:
53
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Q
% Arg:
0
0
30
0
6
0
0
6
12
0
0
0
0
6
0
% R
% Ser:
6
18
12
24
6
36
48
24
6
18
6
12
12
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
6
0
0
12
0
0
0
% T
% Val:
0
6
12
6
12
6
0
0
6
0
0
42
24
12
6
% V
% Trp:
0
12
0
0
0
0
0
0
0
6
0
0
6
0
0
% W
% Tyr:
0
0
0
0
6
6
0
0
0
0
0
0
6
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _