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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
24.85
Human Site:
S24
Identified Species:
34.17
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S24
V
N
G
L
Y
S
S
S
D
D
V
I
E
L
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S108
V
N
G
L
Y
S
S
S
D
D
V
I
E
L
T
Dog
Lupus familis
XP_532876
440
48280
S24
A
N
G
L
Y
S
S
S
D
D
V
I
E
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S24
V
S
G
L
Y
S
S
S
D
D
V
I
E
L
T
Rat
Rattus norvegicus
Q63081
440
48155
S24
V
S
A
L
Y
S
S
S
D
D
V
I
E
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
A22
S
A
G
G
A
A
G
A
V
P
V
F
Q
A
R
Chicken
Gallus gallus
Q8JG64
505
56163
A24
L
L
A
L
S
A
G
A
S
D
V
V
E
L
S
Frog
Xenopus laevis
NP_001086643
442
47765
S24
A
S
A
M
Y
S
P
S
D
D
V
I
E
L
T
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S24
A
Y
G
L
Y
T
S
S
D
D
V
V
E
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
V25
S
A
E
A
E
V
K
V
E
E
G
V
L
V
A
Honey Bee
Apis mellifera
XP_395981
427
47177
V23
C
L
Y
S
N
S
D
V
I
N
L
K
P
N
N
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
K23
V
C
G
M
Y
S
K
K
D
D
V
V
E
L
T
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
A15
I
A
V
G
A
A
S
A
L
F
D
T
S
D
D
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
K20
N
P
S
N
F
K
S
K
V
L
N
S
N
G
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
Red Bread Mold
Neurospora crassa
Q92249
369
39263
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
13.3
33.3
66.6
66.6
N.A.
0
6.6
66.6
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
93.3
N.A.
33.3
66.6
80
80
N.A.
26.6
20
80
26.6
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
0
0
0
P-Site Similarity:
13.3
N.A.
N.A.
0
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
18
18
6
12
18
0
18
0
0
0
0
0
6
6
% A
% Cys:
6
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
48
53
6
0
0
6
6
% D
% Glu:
0
0
6
0
6
0
0
0
6
6
0
0
53
0
0
% E
% Phe:
0
0
0
0
6
0
0
0
0
6
0
6
0
0
0
% F
% Gly:
0
0
42
12
0
0
12
0
0
0
6
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
0
0
0
0
0
6
0
0
36
0
0
0
% I
% Lys:
0
0
0
0
0
6
12
12
0
0
0
6
0
0
0
% K
% Leu:
6
12
0
42
0
0
0
0
6
6
6
0
6
53
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
18
0
6
6
0
0
0
0
6
6
0
6
6
12
% N
% Pro:
0
6
0
0
0
0
6
0
0
6
0
0
6
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% R
% Ser:
12
18
6
6
6
48
48
42
6
0
0
6
6
0
6
% S
% Thr:
0
0
0
0
0
6
0
0
0
0
0
6
0
0
42
% T
% Val:
30
0
6
0
0
6
0
12
12
0
59
24
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
6
0
48
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _