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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
22.42
Human Site:
S259
Identified Species:
30.83
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S259
Y
D
G
G
R
T
R
S
D
I
V
S
R
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S343
Y
D
G
G
R
T
R
S
D
I
V
S
R
A
L
Dog
Lupus familis
XP_532876
440
48280
S259
Y
E
G
G
R
T
R
S
D
I
V
S
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S259
Y
D
G
G
R
T
R
S
D
I
V
S
R
A
L
Rat
Rattus norvegicus
Q63081
440
48155
S259
Y
D
G
G
R
T
R
S
D
I
V
S
R
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
L254
N
A
P
P
P
E
L
L
E
I
V
D
E
A
V
Chicken
Gallus gallus
Q8JG64
505
56163
D257
K
D
L
I
Q
G
K
D
L
L
V
A
Y
Y
D
Frog
Xenopus laevis
NP_001086643
442
47765
A261
Y
D
G
G
R
N
R
A
D
I
V
A
R
A
L
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S259
Y
Q
G
G
R
T
R
S
D
I
V
A
R
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
E310
E
F
F
G
M
N
K
E
E
V
P
T
I
R
L
Honey Bee
Apis mellifera
XP_395981
427
47177
V251
G
R
T
S
S
D
I
V
N
W
A
L
E
K
L
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
R259
A
Q
D
Y
D
G
G
R
Q
S
S
D
I
V
A
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
P243
Y
P
T
L
R
Y
F
P
A
G
V
K
D
A
N
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
P248
L
E
S
N
V
A
P
P
E
V
T
E
L
T
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
K205
N
L
D
A
D
A
H
K
A
L
G
E
K
Y
G
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
V161
R
S
Y
V
K
K
F
V
R
I
D
T
L
G
S
Red Bread Mold
Neurospora crassa
Q92249
369
39263
G213
K
K
S
A
A
E
Y
G
V
S
G
F
P
T
I
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
20
13.3
80
86.6
N.A.
13.3
6.6
0
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
40
93.3
93.3
N.A.
40
13.3
0
26.6
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
0
6.6
0
P-Site Similarity:
20
N.A.
N.A.
13.3
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
12
6
12
0
6
12
0
6
18
0
53
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
12
0
12
6
0
6
42
0
6
12
6
0
6
% D
% Glu:
6
12
0
0
0
12
0
6
18
0
0
12
12
0
0
% E
% Phe:
0
6
6
0
0
0
12
0
0
0
0
6
0
0
0
% F
% Gly:
6
0
42
48
0
12
6
6
0
6
12
0
0
6
12
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
0
6
0
0
53
0
0
12
0
6
% I
% Lys:
12
6
0
0
6
6
12
6
0
0
0
6
6
6
0
% K
% Leu:
6
6
6
6
0
0
6
6
6
12
0
6
12
0
53
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
6
0
12
0
0
6
0
0
0
0
0
6
% N
% Pro:
0
6
6
6
6
0
6
12
0
0
6
0
6
0
0
% P
% Gln:
0
12
0
0
6
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
6
6
0
0
48
0
42
6
6
0
0
0
42
6
0
% R
% Ser:
0
6
12
6
6
0
0
36
0
12
6
30
0
0
6
% S
% Thr:
0
0
12
0
0
36
0
0
0
0
6
12
0
12
0
% T
% Val:
0
0
0
6
6
0
0
12
6
12
59
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% W
% Tyr:
48
0
6
6
0
6
6
0
0
0
0
0
6
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _