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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
27.58
Human Site:
S270
Identified Species:
37.92
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S270
S
R
A
L
D
L
F
S
D
N
A
P
P
P
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S354
S
R
A
L
D
L
F
S
D
N
A
P
P
P
E
Dog
Lupus familis
XP_532876
440
48280
S270
S
R
A
L
D
L
F
S
E
N
A
P
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S270
S
R
A
L
D
L
F
S
D
N
A
P
P
P
E
Rat
Rattus norvegicus
Q63081
440
48155
S270
S
R
A
L
D
L
F
S
D
N
A
P
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
T265
D
E
A
V
A
K
K
T
C
E
D
H
Q
L
C
Chicken
Gallus gallus
Q8JG64
505
56163
E268
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
N
Frog
Xenopus laevis
NP_001086643
442
47765
S272
A
R
A
L
D
L
F
S
E
N
A
P
P
P
E
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S270
A
R
A
L
E
L
Y
S
D
N
I
P
A
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
E321
T
I
R
L
I
K
L
E
E
D
M
A
K
Y
K
Honey Bee
Apis mellifera
XP_395981
427
47177
V262
L
E
K
L
A
E
N
V
P
A
P
E
V
L
Q
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
A270
D
I
V
A
W
A
S
A
R
A
Q
E
N
M
P
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
E254
K
D
A
N
S
A
E
E
Y
D
G
G
R
T
A
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
M259
E
L
T
G
P
D
V
M
E
E
K
C
G
S
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
F216
E
K
Y
G
V
S
G
F
P
T
L
K
F
F
P
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
K172
T
L
G
S
L
L
R
K
S
P
K
L
S
V
V
Red Bread Mold
Neurospora crassa
Q92249
369
39263
P224
F
P
T
I
K
F
F
P
K
G
S
T
T
P
E
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
6.6
13.3
86.6
66.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
26.6
100
86.6
N.A.
33.3
13.3
6.6
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
0
6.6
20
P-Site Similarity:
6.6
N.A.
N.A.
6.6
13.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
53
6
12
12
0
6
0
12
42
6
6
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
6
% C
% Asp:
12
6
0
6
36
12
0
0
30
12
6
0
0
0
0
% D
% Glu:
12
12
0
0
6
6
6
18
24
12
0
12
0
0
48
% E
% Phe:
6
0
0
0
0
6
42
6
0
0
0
0
6
6
0
% F
% Gly:
0
0
6
12
0
0
6
0
0
6
6
6
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
12
0
6
6
0
0
0
0
0
6
0
0
0
0
% I
% Lys:
6
6
6
0
6
12
6
6
12
0
12
12
6
0
6
% K
% Leu:
6
12
0
53
6
48
6
0
0
0
6
6
0
12
0
% L
% Met:
0
0
0
0
0
0
0
6
0
0
6
0
0
6
0
% M
% Asn:
0
0
0
6
0
0
6
0
0
48
0
0
6
0
6
% N
% Pro:
0
6
0
0
6
0
0
6
12
6
6
42
36
48
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
6
% Q
% Arg:
0
42
6
0
0
0
6
0
6
0
0
0
6
0
0
% R
% Ser:
30
0
0
6
6
6
6
42
6
0
6
0
6
12
0
% S
% Thr:
12
0
12
0
0
0
0
6
0
6
0
6
6
6
0
% T
% Val:
0
0
6
6
12
0
6
6
0
0
0
0
6
6
6
% V
% Trp:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
12
0
0
0
12
0
6
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _