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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
26.97
Human Site:
S315
Identified Species:
37.08
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S315
T
G
A
A
G
R
N
S
Y
L
E
V
L
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S399
T
G
A
A
G
R
N
S
Y
L
E
V
L
L
K
Dog
Lupus familis
XP_532876
440
48280
S315
T
G
A
A
G
R
N
S
Y
L
E
V
L
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S315
T
G
A
A
G
R
N
S
Y
L
E
V
L
L
K
Rat
Rattus norvegicus
Q63081
440
48155
S315
T
G
A
T
G
R
N
S
Y
L
E
V
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
M306
A
D
K
Y
K
K
K
M
W
G
W
L
W
T
E
Chicken
Gallus gallus
Q8JG64
505
56163
K333
I
R
T
A
K
G
D
K
F
V
M
Q
E
E
F
Frog
Xenopus laevis
NP_001086643
442
47765
S317
T
G
A
A
G
R
N
S
Y
L
E
V
M
L
K
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S315
T
G
A
S
G
R
N
S
Y
L
E
V
M
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K386
S
V
A
L
D
K
S
K
S
V
L
V
E
F
Y
Honey Bee
Apis mellifera
XP_395981
427
47177
G304
C
Q
S
E
C
R
N
G
Y
L
K
I
L
N
E
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
N318
C
Q
S
E
C
R
N
N
Y
L
A
M
L
K
E
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
T291
L
I
E
Q
K
V
L
T
D
S
C
D
V
K
P
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
A296
L
E
Q
L
L
S
V
A
E
K
F
K
R
S
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
R253
N
E
K
S
G
T
S
R
D
S
K
G
Q
L
T
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
K210
D
F
Y
S
I
S
N
K
K
L
K
Q
L
T
D
Red Bread Mold
Neurospora crassa
Q92249
369
39263
D261
R
T
P
G
G
G
L
D
T
V
A
G
T
I
A
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
0
6.6
93.3
73.3
N.A.
13.3
33.3
33.3
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
26.6
26.6
100
86.6
N.A.
40
60
60
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
13.3
20
6.6
P-Site Similarity:
6.6
N.A.
N.A.
33.3
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
48
36
0
0
0
6
0
0
12
0
0
0
6
% A
% Cys:
12
0
0
0
12
0
0
0
0
0
6
0
0
0
0
% C
% Asp:
6
6
0
0
6
0
6
6
12
0
0
6
0
0
6
% D
% Glu:
0
12
6
12
0
0
0
0
6
0
42
0
12
6
18
% E
% Phe:
0
6
0
0
0
0
0
0
6
0
6
0
0
6
6
% F
% Gly:
0
42
0
6
53
12
0
6
0
6
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
0
0
6
0
0
0
0
0
0
6
0
6
0
% I
% Lys:
0
0
12
0
18
12
6
18
6
6
18
6
0
18
36
% K
% Leu:
12
0
0
12
6
0
12
0
0
59
6
6
48
42
0
% L
% Met:
0
0
0
0
0
0
0
6
0
0
6
6
12
0
0
% M
% Asn:
6
0
0
0
0
0
59
6
0
0
0
0
0
6
0
% N
% Pro:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
12
6
6
0
0
0
0
0
0
0
12
6
0
0
% Q
% Arg:
6
6
0
0
0
53
0
6
0
0
0
0
6
0
0
% R
% Ser:
6
0
12
18
0
12
12
42
6
12
0
0
0
6
0
% S
% Thr:
42
6
6
6
0
6
0
6
6
0
0
0
6
12
12
% T
% Val:
0
6
0
0
0
6
6
0
0
18
0
48
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
6
0
6
0
0
% W
% Tyr:
0
0
6
6
0
0
0
0
53
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _