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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
37.27
Human Site:
S375
Identified Species:
51.25
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S375
K
F
A
L
L
K
G
S
F
S
E
Q
G
I
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S459
K
F
A
L
L
K
G
S
F
S
E
Q
G
I
N
Dog
Lupus familis
XP_532876
440
48280
S375
K
F
A
L
L
K
G
S
F
S
E
Q
G
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S375
K
F
A
L
L
K
G
S
F
S
E
Q
G
I
N
Rat
Rattus norvegicus
Q63081
440
48155
S375
K
F
A
L
L
K
G
S
F
S
E
Q
G
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
L363
I
N
E
F
L
R
E
L
S
F
G
R
G
S
T
Chicken
Gallus gallus
Q8JG64
505
56163
K420
K
Y
K
E
L
G
E
K
L
S
K
D
P
N
I
Frog
Xenopus laevis
NP_001086643
442
47765
S377
K
F
A
L
L
K
G
S
F
S
E
Q
G
I
N
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S375
K
F
A
L
L
K
G
S
F
S
E
T
G
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
K444
I
S
S
F
P
T
I
K
Y
F
R
K
E
D
N
Honey Bee
Apis mellifera
XP_395981
427
47177
S364
K
Y
S
L
L
K
G
S
F
S
Y
D
G
I
N
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
S378
K
Y
A
V
L
K
G
S
F
G
K
D
G
I
H
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
S347
V
G
R
G
S
S
E
S
I
R
G
D
A
L
P
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
H352
K
S
A
F
E
L
E
H
I
V
E
F
V
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
Y309
T
T
R
Y
G
K
L
Y
L
K
L
A
K
S
Y
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
N266
E
Y
E
G
N
S
I
N
K
N
D
I
S
K
F
Red Bread Mold
Neurospora crassa
Q92249
369
39263
S317
L
R
V
L
D
K
L
S
K
S
E
G
Y
A
T
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
20
100
86.6
N.A.
6.6
73.3
60
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
33.3
100
93.3
N.A.
26.6
86.6
86.6
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
20
N.A.
N.A.
6.6
0
33.3
P-Site Similarity:
20
N.A.
N.A.
6.6
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
53
0
0
0
0
0
0
0
0
6
6
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
0
0
0
0
0
6
24
0
6
0
% D
% Glu:
6
0
12
6
6
0
24
0
0
0
53
0
6
0
6
% E
% Phe:
0
42
0
18
0
0
0
0
53
12
0
6
0
0
6
% F
% Gly:
0
6
0
12
6
6
53
0
0
6
12
6
59
0
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
12
% H
% Ile:
12
0
0
0
0
0
12
0
12
0
0
6
0
53
6
% I
% Lys:
65
0
6
0
0
65
0
12
12
6
12
6
6
12
0
% K
% Leu:
6
0
0
53
65
6
12
6
12
0
6
0
0
6
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
6
0
0
6
0
6
0
0
0
6
48
% N
% Pro:
0
0
0
0
6
0
0
0
0
0
0
0
6
0
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% Q
% Arg:
0
6
12
0
0
6
0
0
0
6
6
6
0
0
0
% R
% Ser:
0
12
12
0
6
12
0
65
6
59
0
0
6
12
0
% S
% Thr:
6
6
0
0
0
6
0
0
0
0
0
6
0
0
12
% T
% Val:
6
0
6
6
0
0
0
0
0
6
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
6
0
0
0
6
6
0
6
0
6
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _