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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
36.06
Human Site:
S389
Identified Species:
49.58
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S389
N
E
F
L
R
E
L
S
F
G
R
G
S
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S473
N
E
F
L
R
E
L
S
F
G
R
G
S
T
A
Dog
Lupus familis
XP_532876
440
48280
S389
N
E
F
L
R
E
L
S
F
G
R
G
S
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S389
N
E
F
L
R
E
L
S
F
G
R
G
S
T
A
Rat
Rattus norvegicus
Q63081
440
48155
S389
N
E
F
L
R
E
L
S
F
G
R
G
S
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
A377
T
A
P
V
G
G
G
A
F
P
K
I
N
T
V
Chicken
Gallus gallus
Q8JG64
505
56163
A434
I
V
I
A
K
M
D
A
T
A
N
D
V
P
S
Frog
Xenopus laevis
NP_001086643
442
47765
S391
N
E
F
L
R
E
L
S
Y
G
R
G
S
T
S
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S389
H
E
F
L
R
E
L
S
V
G
R
G
S
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
L458
N
K
V
I
D
F
N
L
D
R
T
L
D
D
F
Honey Bee
Apis mellifera
XP_395981
427
47177
S378
N
E
F
L
R
D
L
S
Y
G
R
G
G
T
A
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
S392
H
E
F
L
R
D
L
S
Y
G
K
G
R
T
S
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
P361
P
S
I
E
T
K
E
P
W
D
G
K
D
G
E
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
G366
E
A
G
R
G
G
K
G
N
L
P
L
N
G
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
Y323
Y
I
E
K
G
S
D
Y
A
S
K
E
T
E
R
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
I280
F
L
R
D
T
F
S
I
T
P
N
E
G
P
F
Red Bread Mold
Neurospora crassa
Q92249
369
39263
E331
T
K
E
F
A
R
L
E
G
I
L
K
K
G
G
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
0
86.6
86.6
N.A.
6.6
80
60
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
40
20
100
93.3
N.A.
20
93.3
93.3
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
0
0
6.6
P-Site Similarity:
6.6
N.A.
N.A.
13.3
0
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
6
6
0
0
12
6
6
0
0
0
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
6
12
12
0
6
6
0
6
12
6
0
% D
% Glu:
6
53
12
6
0
42
6
6
0
0
0
12
0
6
6
% E
% Phe:
6
0
53
6
0
12
0
0
36
0
0
0
0
0
12
% F
% Gly:
0
0
6
0
18
12
6
6
6
53
6
53
12
18
6
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
12
6
0
0
0
6
0
6
0
6
0
0
0
% I
% Lys:
0
12
0
6
6
6
6
0
0
0
18
12
6
0
0
% K
% Leu:
0
6
0
53
0
0
59
6
0
6
6
12
0
0
0
% L
% Met:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% M
% Asn:
48
0
0
0
0
0
6
0
6
0
12
0
12
0
6
% N
% Pro:
6
0
6
0
0
0
0
6
0
12
6
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
6
6
53
6
0
0
0
6
48
0
6
0
6
% R
% Ser:
0
6
0
0
0
6
6
53
0
6
0
0
42
0
18
% S
% Thr:
12
0
0
0
12
0
0
0
12
0
6
0
6
59
0
% T
% Val:
0
6
6
6
0
0
0
0
6
0
0
0
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
6
18
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _