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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
39.09
Human Site:
S428
Identified Species:
53.75
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
S428
V
E
D
D
I
D
L
S
D
V
E
L
D
D
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
S512
V
E
D
D
I
D
L
S
D
V
E
L
D
D
L
Dog
Lupus familis
XP_532876
440
48280
S428
V
E
D
D
I
D
L
S
D
V
E
L
D
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
S428
V
E
D
D
I
D
L
S
D
V
E
L
D
D
L
Rat
Rattus norvegicus
Q63081
440
48155
S428
V
E
D
D
I
D
L
S
D
V
E
L
D
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
D408
D
L
S
D
V
E
L
D
D
L
G
K
D
E
L
Chicken
Gallus gallus
Q8JG64
505
56163
T485
L
K
R
E
A
T
S
T
P
V
L
Q
E
E
D
Frog
Xenopus laevis
NP_001086643
442
47765
S430
A
E
D
D
I
D
L
S
D
V
E
L
D
D
I
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
S428
M
E
D
D
I
D
L
S
D
V
D
L
D
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
E489
E
E
T
E
E
E
E
E
A
P
K
K
D
E
L
Honey Bee
Apis mellifera
XP_395981
427
47177
S417
Q
E
E
E
I
D
L
S
D
I
D
L
D
E
K
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
S431
A
E
D
D
I
D
L
S
D
I
D
L
D
K
T
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
E392
D
D
E
D
E
D
V
E
V
E
K
K
D
E
L
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
L397
I
E
E
D
E
F
S
L
E
E
L
M
G
E
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
L354
L
T
L
K
R
N
I
L
T
T
F
V
A
S
S
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
S311
I
K
K
N
H
S
S
S
G
N
K
H
D
E
L
Red Bread Mold
Neurospora crassa
Q92249
369
39263
A362
R
K
F
V
E
K
A
A
E
E
A
K
E
E
L
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
6.6
86.6
86.6
N.A.
20
53.3
66.6
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
60
46.6
93.3
100
N.A.
46.6
86.6
80
60
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
13.3
N.A.
N.A.
0
20
6.6
P-Site Similarity:
46.6
N.A.
N.A.
26.6
53.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
6
0
6
6
6
0
6
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
48
65
0
59
0
6
59
0
18
0
77
42
12
% D
% Glu:
6
65
18
18
24
12
6
12
12
18
36
0
12
48
0
% E
% Phe:
0
0
6
0
0
6
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
6
0
6
0
6
0
0
% G
% His:
0
0
0
0
6
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
12
0
0
0
53
0
6
0
0
12
0
0
0
0
6
% I
% Lys:
0
18
6
6
0
6
0
0
0
0
18
24
0
6
6
% K
% Leu:
12
6
6
0
0
0
59
12
0
6
12
53
0
0
65
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
6
0
6
0
0
0
6
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
6
0
6
0
6
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
6
0
0
6
18
59
0
0
0
0
0
6
6
% S
% Thr:
0
6
6
0
0
6
0
6
6
6
0
0
0
0
6
% T
% Val:
30
0
0
6
6
0
6
0
6
48
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _