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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
34.24
Human Site:
T239
Identified Species:
47.08
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
T239
Y
G
I
R
G
F
P
T
I
K
I
F
Q
K
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
T323
Y
G
I
R
G
F
P
T
I
K
I
F
Q
K
G
Dog
Lupus familis
XP_532876
440
48280
T239
Y
G
I
R
G
F
P
T
I
K
I
F
Q
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
T239
Y
G
I
K
G
F
P
T
I
K
I
F
Q
K
G
Rat
Rattus norvegicus
Q63081
440
48155
T239
Y
G
I
K
G
F
P
T
I
K
I
F
Q
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
S234
Y
D
G
G
R
T
R
S
D
I
V
S
R
A
L
Chicken
Gallus gallus
Q8JG64
505
56163
N237
I
K
K
F
I
Q
E
N
I
F
G
I
C
P
H
Frog
Xenopus laevis
NP_001086643
442
47765
T241
Y
G
I
R
G
F
P
T
I
K
I
F
Q
K
G
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
T239
F
G
I
R
G
F
P
T
I
K
V
F
R
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
T290
R
D
D
I
L
F
V
T
I
S
S
D
E
E
D
Honey Bee
Apis mellifera
XP_395981
427
47177
G231
T
I
K
Y
F
A
P
G
K
K
S
T
D
F
V
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
T239
F
A
I
R
G
F
P
T
I
K
Y
F
A
P
G
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
V223
L
G
A
L
D
A
T
V
H
T
V
T
A
S
R
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
R228
P
I
P
Y
E
G
A
R
T
A
S
A
I
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
A185
A
P
T
Y
E
K
V
A
T
V
F
K
Q
E
E
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
T141
E
V
Y
S
G
A
R
T
L
A
P
I
V
D
F
Red Bread Mold
Neurospora crassa
Q92249
369
39263
I193
T
F
A
S
D
P
E
I
T
I
A
K
V
D
A
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
6.6
6.6
100
80
N.A.
20
13.3
66.6
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
6.6
100
100
N.A.
33.3
13.3
73.3
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
6.6
N.A.
N.A.
13.3
20
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
12
0
0
18
6
6
0
12
6
6
12
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
0
12
6
0
12
0
0
0
6
0
0
6
6
12
6
% D
% Glu:
6
0
0
0
12
0
12
0
0
0
0
0
6
18
6
% E
% Phe:
12
6
0
6
6
53
0
0
0
6
6
48
0
6
6
% F
% Gly:
0
48
6
6
53
6
0
6
0
0
6
0
0
0
48
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
6
% H
% Ile:
6
12
48
6
6
0
0
6
59
12
36
12
6
0
0
% I
% Lys:
0
6
12
12
0
6
0
0
6
53
0
12
0
42
0
% K
% Leu:
6
0
0
6
6
0
0
0
6
0
0
0
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% N
% Pro:
6
6
6
0
0
6
53
0
0
0
6
0
0
12
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
0
42
0
0
% Q
% Arg:
6
0
0
36
6
0
12
6
0
0
0
0
12
0
6
% R
% Ser:
0
0
0
12
0
0
0
6
0
6
18
6
0
6
6
% S
% Thr:
12
0
6
0
0
6
6
59
18
6
0
12
0
0
0
% T
% Val:
0
6
0
0
0
0
12
6
0
6
18
0
12
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
42
0
6
18
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _