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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
16.97
Human Site:
T405
Identified Species:
23.33
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
T405
V
G
G
G
A
F
P
T
I
V
E
R
E
P
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
T489
V
G
G
G
A
F
P
T
I
V
E
R
E
P
W
Dog
Lupus familis
XP_532876
440
48280
T405
V
G
G
G
A
F
P
T
I
S
T
R
E
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
T405
V
G
G
G
S
F
P
T
I
T
P
R
E
P
W
Rat
Rattus norvegicus
Q63081
440
48155
N405
V
G
G
G
S
F
P
N
I
T
P
R
E
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
E393
P
W
D
G
K
D
G
E
L
P
L
E
D
D
I
Chicken
Gallus gallus
Q8JG64
505
56163
T450
Y
E
V
R
G
F
P
T
I
Y
F
A
P
A
G
Frog
Xenopus laevis
NP_001086643
442
47765
K407
V
G
G
G
A
I
P
K
I
N
T
V
E
P
W
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
K405
V
G
G
G
A
L
P
K
I
N
T
V
Q
A
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
E474
K
F
L
D
A
N
G
E
V
A
D
S
E
P
V
Honey Bee
Apis mellifera
XP_395981
427
47177
T394
L
K
G
A
Q
L
P
T
I
L
E
T
K
S
W
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
K408
L
R
G
D
G
F
P
K
I
Q
K
T
E
K
W
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
L377
P
E
E
D
D
I
D
L
S
D
F
D
M
D
D
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
W382
E
I
V
K
T
E
P
W
D
G
K
D
G
E
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
I339
G
R
V
L
G
K
S
I
S
P
V
K
A
D
E
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
Y296
R
R
S
E
Y
I
A
Y
L
K
T
G
K
K
P
Red Bread Mold
Neurospora crassa
Q92249
369
39263
L347
A
P
A
K
V
D
E
L
T
V
K
V
N
V
L
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
73.3
N.A.
6.6
26.6
66.6
53.3
N.A.
20
40
40
0
P-Site Similarity:
100
N.A.
100
86.6
N.A.
86.6
80
N.A.
20
26.6
66.6
60
N.A.
33.3
60
53.3
0
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
0
0
6.6
P-Site Similarity:
13.3
N.A.
N.A.
6.6
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
6
36
0
6
0
0
6
0
6
6
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
18
6
12
6
0
6
6
6
12
6
18
6
% D
% Glu:
6
12
6
6
0
6
6
12
0
0
18
6
48
6
6
% E
% Phe:
0
6
0
0
0
42
0
0
0
0
12
0
0
0
0
% F
% Gly:
6
42
53
48
18
0
12
0
0
6
0
6
6
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
0
0
18
0
6
59
0
0
0
0
0
12
% I
% Lys:
6
6
0
12
6
6
0
18
0
6
18
6
12
12
0
% K
% Leu:
12
0
6
6
0
12
0
12
12
6
6
0
0
0
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
6
0
6
0
12
0
0
6
0
0
% N
% Pro:
12
6
0
0
0
0
65
0
0
12
12
0
6
42
6
% P
% Gln:
0
0
0
0
6
0
0
0
0
6
0
0
6
0
0
% Q
% Arg:
6
18
0
6
0
0
0
0
0
0
0
30
0
0
0
% R
% Ser:
0
0
6
0
12
0
6
0
12
6
0
6
0
6
0
% S
% Thr:
0
0
0
0
6
0
0
36
6
12
24
12
0
0
0
% T
% Val:
42
0
18
0
6
0
0
0
6
18
6
18
0
6
6
% V
% Trp:
0
6
0
0
0
0
0
6
0
0
0
0
0
0
53
% W
% Tyr:
6
0
0
0
6
0
0
6
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _