KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
30.61
Human Site:
Y114
Identified Species:
42.08
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
Y114
N
K
N
R
P
E
D
Y
Q
G
G
R
T
G
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
Y198
N
K
N
R
P
E
D
Y
Q
G
G
R
T
G
E
Dog
Lupus familis
XP_532876
440
48280
Y114
N
K
N
R
P
E
D
Y
Q
G
S
R
T
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
Y114
N
K
N
K
P
E
D
Y
Q
G
G
R
T
G
E
Rat
Rattus norvegicus
Q63081
440
48155
Y114
N
K
N
K
P
E
D
Y
Q
G
G
R
T
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
V110
L
S
A
L
R
P
L
V
K
D
R
L
S
G
R
Chicken
Gallus gallus
Q8JG64
505
56163
D114
G
E
E
S
G
T
Y
D
G
P
R
T
A
D
G
Frog
Xenopus laevis
NP_001086643
442
47765
Y114
N
K
N
K
P
D
D
Y
Q
G
G
R
T
A
D
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
Y114
N
K
H
K
P
E
D
Y
Q
G
G
R
T
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
E154
E
Q
F
L
K
D
N
E
I
A
I
I
G
F
F
Honey Bee
Apis mellifera
XP_395981
427
47177
N110
D
N
K
P
E
D
Y
N
G
P
R
T
A
A
G
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
Y113
D
K
K
K
P
T
D
Y
N
G
Q
R
T
A
Q
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
A102
P
T
I
K
V
F
G
A
N
K
A
S
P
T
D
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
Y107
D
V
K
P
I
A
E
Y
A
L
K
Q
I
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
K64
K
L
A
P
E
Y
E
K
L
G
A
S
F
K
K
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
K20
L
F
I
M
N
E
V
K
A
Q
N
F
Y
D
S
Red Bread Mold
Neurospora crassa
Q92249
369
39263
K71
A
T
A
L
E
Y
A
K
D
K
V
Q
I
A
K
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
6.6
0
73.3
73.3
N.A.
0
0
46.6
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
20
6.6
93.3
93.3
N.A.
20
13.3
66.6
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
26.6
N.A.
N.A.
20
6.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
18
0
0
6
6
6
12
6
12
0
12
24
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
0
0
0
0
18
48
6
6
6
0
0
0
12
12
% D
% Glu:
6
6
6
0
18
42
12
6
0
0
0
0
0
0
30
% E
% Phe:
0
6
6
0
0
6
0
0
0
0
0
6
6
6
6
% F
% Gly:
6
0
0
0
6
0
6
0
12
53
36
0
6
36
12
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
6
0
0
0
6
0
6
6
12
0
0
% I
% Lys:
6
48
18
36
6
0
0
18
6
12
6
0
0
12
12
% K
% Leu:
12
6
0
18
0
0
6
0
6
6
0
6
0
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
42
6
36
0
6
0
6
6
12
0
6
0
0
6
0
% N
% Pro:
6
0
0
18
48
6
0
0
0
12
0
0
6
0
0
% P
% Gln:
0
6
0
0
0
0
0
0
42
6
6
12
0
0
12
% Q
% Arg:
0
0
0
18
6
0
0
0
0
0
18
48
0
0
6
% R
% Ser:
0
6
0
6
0
0
0
0
0
0
6
12
6
0
6
% S
% Thr:
0
12
0
0
0
12
0
0
0
0
0
12
48
6
0
% T
% Val:
0
6
0
0
6
0
6
6
0
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
12
53
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _