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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA6
All Species:
29.09
Human Site:
Y327
Identified Species:
40
UniProt:
Q15084
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15084
NP_005733.1
440
48121
Y327
L
L
K
L
A
D
K
Y
K
K
K
M
W
G
W
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095159
524
57323
Y411
L
L
K
M
A
D
K
Y
K
K
K
M
W
G
W
Dog
Lupus familis
XP_532876
440
48280
Y327
L
L
K
L
A
D
K
Y
K
K
K
M
W
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q922R8
440
48082
Y327
L
L
K
L
A
D
K
Y
K
K
K
M
W
G
W
Rat
Rattus norvegicus
Q63081
440
48155
Y327
L
L
K
L
A
D
K
Y
K
K
K
M
W
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505713
415
44653
F318
W
T
E
A
G
A
Q
F
E
L
E
N
A
L
G
Chicken
Gallus gallus
Q8JG64
505
56163
K345
E
E
F
S
R
D
G
K
A
L
E
R
F
L
Q
Frog
Xenopus laevis
NP_001086643
442
47765
Y329
M
L
K
M
A
E
K
Y
K
K
K
M
W
G
W
Zebra Danio
Brachydanio rerio
NP_922915
440
48022
H327
M
K
T
M
A
E
K
H
K
K
K
M
W
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
G398
E
F
Y
A
P
W
C
G
H
C
K
Q
L
A
P
Honey Bee
Apis mellifera
XP_395981
427
47177
Y316
L
N
E
L
G
E
K
Y
K
Q
K
M
W
G
W
Nematode Worm
Caenorhab. elegans
Q11067
440
47710
F330
L
K
E
Q
S
E
K
F
K
K
N
L
W
G
W
Sea Urchin
Strong. purpuratus
XP_790496
399
42463
S303
V
K
P
L
C
I
I
S
V
L
P
H
I
L
D
Poplar Tree
Populus trichocarpa
XP_002320494
404
43880
W308
R
S
P
Y
S
Y
V
W
A
A
A
G
K
Q
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
I265
Q
L
T
S
K
A
G
I
V
E
S
L
D
A
L
Baker's Yeast
Sacchar. cerevisiae
Q12404
318
36390
Y222
L
T
D
M
N
P
T
Y
E
K
T
P
E
I
F
Red Bread Mold
Neurospora crassa
Q92249
369
39263
I273
T
I
A
A
L
D
E
I
V
A
K
Y
T
G
G
Conservation
Percent
Protein Identity:
100
N.A.
82.8
94.5
N.A.
95.4
94.7
N.A.
81.1
20.7
82.3
76.1
N.A.
21.5
59.3
55.6
47
Protein Similarity:
100
N.A.
83.4
97.5
N.A.
97.9
97.5
N.A.
86.8
38.4
92
88.8
N.A.
38.9
76.3
73.4
63.8
P-Site Identity:
100
N.A.
93.3
100
N.A.
100
100
N.A.
0
6.6
80
60
N.A.
6.6
66.6
46.6
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
20
100
86.6
N.A.
6.6
86.6
80
13.3
Percent
Protein Identity:
44.3
N.A.
N.A.
31.1
23.8
31.1
Protein Similarity:
63.1
N.A.
N.A.
47.9
39.7
48.4
P-Site Identity:
0
N.A.
N.A.
6.6
20
20
P-Site Similarity:
13.3
N.A.
N.A.
20
40
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
18
42
12
0
0
12
12
6
0
6
12
0
% A
% Cys:
0
0
0
0
6
0
6
0
0
6
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
42
0
0
0
0
0
0
6
0
6
% D
% Glu:
12
6
18
0
0
24
6
0
12
6
12
0
6
0
0
% E
% Phe:
0
6
6
0
0
0
0
12
0
0
0
0
6
0
6
% F
% Gly:
0
0
0
0
12
0
12
6
0
0
0
6
0
59
12
% G
% His:
0
0
0
0
0
0
0
6
6
0
0
6
0
0
0
% H
% Ile:
0
6
0
0
0
6
6
12
0
0
0
0
6
6
0
% I
% Lys:
0
18
36
0
6
0
53
6
53
53
59
0
6
0
0
% K
% Leu:
48
42
0
36
6
0
0
0
0
18
0
12
6
18
6
% L
% Met:
12
0
0
24
0
0
0
0
0
0
0
48
0
0
0
% M
% Asn:
0
6
0
0
6
0
0
0
0
0
6
6
0
0
0
% N
% Pro:
0
0
12
0
6
6
0
0
0
0
6
6
0
0
12
% P
% Gln:
6
0
0
6
0
0
6
0
0
6
0
6
0
6
6
% Q
% Arg:
6
0
0
0
6
0
0
0
0
0
0
6
0
0
0
% R
% Ser:
0
6
0
12
12
0
0
6
0
0
6
0
0
0
0
% S
% Thr:
6
12
12
0
0
0
6
0
0
0
6
0
6
0
0
% T
% Val:
6
0
0
0
0
0
6
0
18
0
0
0
0
0
0
% V
% Trp:
6
0
0
0
0
6
0
6
0
0
0
0
53
0
53
% W
% Tyr:
0
0
6
6
0
6
0
48
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _