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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAFAH1B3 All Species: 36.67
Human Site: Y193 Identified Species: 73.33
UniProt: Q15102 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15102 NP_001139411.1 231 25734 Y193 S H H D M Y D Y L H L S R L G
Chimpanzee Pan troglodytes XP_001153890 218 24226 Y180 S H H D M Y D Y L H L S R L G
Rhesus Macaque Macaca mulatta XP_001105561 231 25843 Y193 S H H D M Y D Y L H L S R L G
Dog Lupus familis XP_533656 231 25833 Y193 S H H D M Y D Y L H L S R L G
Cat Felis silvestris
Mouse Mus musculus Q61205 232 25835 Y194 S H H D M Y D Y L H L S R L G
Rat Rattus norvegicus O35263 232 25845 Y194 S H H D M Y D Y L H L S R L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514293 352 39236 F317 S C H D M F D F L H L T S G G
Chicken Gallus gallus Q5ZMS2 229 25549 F194 S Y H D M F D F L H L T G G A
Frog Xenopus laevis NP_001083297 226 25428 Y194 S H H D M Y D Y L H L S R H G
Zebra Danio Brachydanio rerio NP_957352 221 24500 Y193 A H Q D M Y D Y L H L T P H A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXP4 225 25442 Y189 S H H D M F D Y K N L T N A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202823 216 24130 Y190 Y P T D M F D Y L H F T N E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 99.1 96.5 N.A. 95.6 96.1 N.A. 42 62.3 67.5 61.9 N.A. 43.7 N.A. N.A. 51
Protein Similarity: 100 94.3 99.5 97.4 N.A. 96.5 96.9 N.A. 53.4 80 80.5 77.4 N.A. 64.9 N.A. N.A. 68.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 60 53.3 93.3 60 N.A. 60 N.A. N.A. 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 80 80 93.3 73.3 N.A. 80 N.A. N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 17 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 100 0 0 100 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 34 0 17 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 9 17 84 % G
% His: 0 75 84 0 0 0 0 0 0 92 0 0 0 17 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 92 0 92 0 0 50 0 % L
% Met: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 17 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 % R
% Ser: 84 0 0 0 0 0 0 0 0 0 0 59 9 0 0 % S
% Thr: 0 0 9 0 0 0 0 0 0 0 0 42 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 0 0 67 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _