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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
22.12
Human Site:
S1079
Identified Species:
37.44
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
S1079
A
E
A
K
S
K
R
S
L
E
A
I
E
E
K
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
S1079
A
E
A
K
S
K
R
S
L
E
A
I
E
E
K
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
S1079
A
E
A
K
S
K
R
S
L
E
A
I
E
E
K
Dog
Lupus familis
XP_536020
1096
122535
S1080
A
E
A
K
S
K
R
S
L
E
A
I
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
S1080
S
E
A
K
G
K
R
S
L
E
A
I
E
E
K
Rat
Rattus norvegicus
Q62688
1096
122754
S1080
A
E
A
K
G
K
R
S
L
E
A
I
E
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
R1036
S
E
V
S
K
P
R
R
S
L
E
A
I
P
E
Chicken
Gallus gallus
Q2VRL0
637
72514
G622
V
P
L
F
S
K
S
G
G
K
L
E
P
A
S
Frog
Xenopus laevis
Q32NH8
758
87399
F743
K
I
P
P
A
S
L
F
V
H
I
R
V
T
D
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
R769
F
I
H
V
K
V
V
R
R
G
V
H
I
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
V1071
I
E
E
F
S
T
D
V
Q
K
L
M
D
M
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
R1053
L
I
I
R
K
N
G
R
R
F
S
R
V
I
A
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
K669
Y
E
T
A
T
S
L
K
Q
A
H
E
G
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
G854
I
P
L
F
N
M
E
G
E
Q
Y
I
F
C
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
13.3
13.3
0
0
N.A.
13.3
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
20
13.3
6.6
N.A.
33.3
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
43
8
8
0
0
0
0
8
43
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
8
% D
% Glu:
0
65
8
0
0
0
8
0
8
43
8
15
43
43
8
% E
% Phe:
8
0
0
22
0
0
0
8
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
15
0
8
15
8
8
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
8
8
0
0
0
% H
% Ile:
15
22
8
0
0
0
0
0
0
0
8
50
15
8
8
% I
% Lys:
8
0
0
43
22
50
0
8
0
15
0
0
0
8
43
% K
% Leu:
8
0
15
0
0
0
15
0
43
8
15
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
8
8
0
8
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
50
22
15
0
0
15
0
0
0
% R
% Ser:
15
0
0
8
43
15
8
43
8
0
8
0
0
0
8
% S
% Thr:
0
0
8
0
8
8
0
0
0
0
0
0
0
8
15
% T
% Val:
8
0
8
8
0
8
8
8
8
0
8
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _