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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCL1 All Species: 22.12
Human Site: S1079 Identified Species: 37.44
UniProt: Q15111 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15111 NP_006217.3 1095 122728 S1079 A E A K S K R S L E A I E E K
Chimpanzee Pan troglodytes XP_001169560 1095 122728 S1079 A E A K S K R S L E A I E E K
Rhesus Macaque Macaca mulatta XP_001089483 1095 122754 S1079 A E A K S K R S L E A I E E K
Dog Lupus familis XP_536020 1096 122535 S1080 A E A K S K R S L E A I E E K
Cat Felis silvestris
Mouse Mus musculus Q3USB7 1096 122654 S1080 S E A K G K R S L E A I E E K
Rat Rattus norvegicus Q62688 1096 122754 S1080 A E A K G K R S L E A I E E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507313 1051 118878 R1036 S E V S K P R R S L E A I P E
Chicken Gallus gallus Q2VRL0 637 72514 G622 V P L F S K S G G K L E P A S
Frog Xenopus laevis Q32NH8 758 87399 F743 K I P P A S L F V H I R V T D
Zebra Danio Brachydanio rerio A5D6R3 784 89362 R769 F I H V K V V R R G V H I K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 V1071 I E E F S T D V Q K L M D M Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_741067 1068 120024 R1053 L I I R K N G R R F S R V I A
Sea Urchin Strong. purpuratus XP_001178766 684 77475 K669 Y E T A T S L K Q A H E G D I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 G854 I P L F N M E G E Q Y I F C T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 98.7 96.4 N.A. 94.3 94.1 N.A. 62.9 21.7 24.7 27.9 N.A. 20 N.A. 39 35.8
Protein Similarity: 100 100 99.2 98.5 N.A. 96.6 96.6 N.A. 77.1 34.8 40.4 42.3 N.A. 40.2 N.A. 59.4 48.1
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 13.3 13.3 0 0 N.A. 13.3 N.A. 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 26.6 20 13.3 6.6 N.A. 33.3 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 37.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 0 43 8 8 0 0 0 0 8 43 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 8 8 8 % D
% Glu: 0 65 8 0 0 0 8 0 8 43 8 15 43 43 8 % E
% Phe: 8 0 0 22 0 0 0 8 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 0 15 0 8 15 8 8 0 0 8 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 8 8 8 0 0 0 % H
% Ile: 15 22 8 0 0 0 0 0 0 0 8 50 15 8 8 % I
% Lys: 8 0 0 43 22 50 0 8 0 15 0 0 0 8 43 % K
% Leu: 8 0 15 0 0 0 15 0 43 8 15 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 8 0 8 0 % M
% Asn: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 8 8 0 8 0 0 0 0 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 15 8 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 50 22 15 0 0 15 0 0 0 % R
% Ser: 15 0 0 8 43 15 8 43 8 0 8 0 0 0 8 % S
% Thr: 0 0 8 0 8 8 0 0 0 0 0 0 0 8 15 % T
% Val: 8 0 8 8 0 8 8 8 8 0 8 0 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _