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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
23.33
Human Site:
Y572
Identified Species:
39.49
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
Y572
S
R
R
M
S
V
D
Y
N
G
E
Q
K
Q
I
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
Y572
S
R
R
M
S
V
D
Y
N
G
E
Q
K
Q
I
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
Y572
S
R
R
M
S
V
D
Y
N
G
E
Q
K
Q
I
Dog
Lupus familis
XP_536020
1096
122535
Y573
S
R
R
L
S
V
D
Y
N
G
E
Q
K
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
Y573
S
R
R
M
S
G
D
Y
N
G
E
Q
K
H
I
Rat
Rattus norvegicus
Q62688
1096
122754
Y573
S
R
R
V
S
G
D
Y
N
G
E
Q
K
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
N529
K
E
G
V
E
L
P
N
I
V
P
V
K
R
F
Chicken
Gallus gallus
Q2VRL0
637
72514
G183
L
V
S
D
Q
L
I
G
P
S
D
L
N
G
Y
Frog
Xenopus laevis
Q32NH8
758
87399
S304
C
H
Y
F
I
S
S
S
H
N
T
Y
L
M
E
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
T330
Y
I
S
S
S
H
N
T
Y
L
T
K
D
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A537
A
E
A
E
A
A
A
A
N
Y
S
G
S
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
K537
S
T
T
R
R
K
S
K
R
I
Q
L
C
K
E
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
K230
G
K
I
L
I
K
G
K
R
L
P
D
D
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Q415
P
S
V
E
G
Y
I
Q
V
L
Q
Q
G
C
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
6.6
0
0
13.3
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
26.6
13.3
6.6
33.3
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
8
8
8
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
0
0
8
0
0
43
0
0
0
8
8
15
0
0
% D
% Glu:
0
15
0
15
8
0
0
0
0
0
43
0
0
0
22
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
8
0
8
15
8
8
0
43
0
8
8
8
0
% G
% His:
0
8
0
0
0
8
0
0
8
0
0
0
0
22
0
% H
% Ile:
0
8
8
0
15
0
15
0
8
8
0
0
0
0
43
% I
% Lys:
8
8
0
0
0
15
0
15
0
0
0
8
50
8
0
% K
% Leu:
8
0
0
15
0
15
0
0
0
22
0
15
8
0
0
% L
% Met:
0
0
0
29
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
8
8
50
8
0
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
8
0
8
0
15
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
8
0
0
15
50
0
36
0
% Q
% Arg:
0
43
43
8
8
0
0
0
15
0
0
0
0
8
8
% R
% Ser:
50
8
15
8
50
8
15
8
0
8
8
0
8
0
0
% S
% Thr:
0
8
8
0
0
0
0
8
0
0
15
0
0
8
8
% T
% Val:
0
8
8
15
0
29
0
0
8
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
0
8
0
43
8
8
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _