KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCL1
All Species:
35.15
Human Site:
Y823
Identified Species:
59.49
UniProt:
Q15111
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15111
NP_006217.3
1095
122728
Y823
F
E
C
L
Q
P
G
Y
R
H
V
P
L
R
S
Chimpanzee
Pan troglodytes
XP_001169560
1095
122728
Y823
F
E
C
L
Q
P
G
Y
R
H
V
P
L
R
S
Rhesus Macaque
Macaca mulatta
XP_001089483
1095
122754
Y823
F
E
C
L
Q
P
G
Y
R
H
V
P
L
R
S
Dog
Lupus familis
XP_536020
1096
122535
Y824
F
E
C
L
Q
P
G
Y
R
H
V
P
L
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3USB7
1096
122654
Y824
F
E
C
L
Q
P
G
Y
R
H
V
P
L
R
S
Rat
Rattus norvegicus
Q62688
1096
122754
Y824
F
E
C
L
Q
P
G
Y
R
H
V
P
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507313
1051
118878
Y780
F
E
C
L
Q
T
G
Y
R
H
V
P
L
Q
S
Chicken
Gallus gallus
Q2VRL0
637
72514
V416
E
L
K
A
Q
K
F
V
K
H
A
A
N
Q
F
Frog
Xenopus laevis
Q32NH8
758
87399
A537
N
D
F
V
R
H
N
A
W
Q
L
M
R
I
Y
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Y563
S
R
Q
L
S
R
I
Y
P
S
A
Q
R
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
Y781
L
D
G
L
Q
A
G
Y
R
H
V
S
L
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_741067
1068
120024
Y783
F
E
C
L
Q
P
G
Y
R
H
I
Y
L
L
N
Sea Urchin
Strong. purpuratus
XP_001178766
684
77475
T463
Q
P
G
Y
R
H
I
T
L
L
S
N
T
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
V648
L
M
R
V
Y
P
H
V
L
R
Y
K
S
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
98.7
96.4
N.A.
94.3
94.1
N.A.
62.9
21.7
24.7
27.9
N.A.
20
N.A.
39
35.8
Protein Similarity:
100
100
99.2
98.5
N.A.
96.6
96.6
N.A.
77.1
34.8
40.4
42.3
N.A.
40.2
N.A.
59.4
48.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
13.3
0
13.3
N.A.
60
N.A.
73.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
26.6
26.6
13.3
N.A.
73.3
N.A.
86.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
0
0
15
8
0
0
0
% A
% Cys:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
58
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
58
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
15
0
0
0
65
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
15
8
0
0
72
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
15
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
8
0
0
8
0
0
8
0
0
8
0
0
0
% K
% Leu:
15
8
0
72
0
0
0
0
15
8
8
0
65
15
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
8
8
0
15
% N
% Pro:
0
8
0
0
0
58
0
0
8
0
0
50
0
0
0
% P
% Gln:
8
0
8
0
72
0
0
0
0
8
0
8
0
15
8
% Q
% Arg:
0
8
8
0
15
8
0
0
65
8
0
0
15
50
0
% R
% Ser:
8
0
0
0
8
0
0
0
0
8
8
8
8
8
50
% S
% Thr:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
8
% T
% Val:
0
0
0
15
0
0
0
15
0
0
58
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
72
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _