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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCOLCE All Species: 15.15
Human Site: S269 Identified Species: 37.04
UniProt: Q15113 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15113 NP_002584.2 449 47972 S269 T A D G F S A S Y K T L P R G
Chimpanzee Pan troglodytes XP_519264 449 47865 S269 T A D G F S A S Y K T L P R G
Rhesus Macaque Macaca mulatta XP_001104751 451 48350 S269 T A D G F S A S Y K T L P R G
Dog Lupus familis XP_859401 458 48568 S269 T A D G F S A S Y K T L P R G
Cat Felis silvestris
Mouse Mus musculus Q61398 468 50149 G292 P G E D V Q R G P Q S R S D P
Rat Rattus norvegicus O08628 468 50166 G292 P G E D A Q H G P Q S R S D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426680 442 48261 S266 S P P A P I V S E K N E L F I
Frog Xenopus laevis P98070 707 80655 P517 E V D E C S R P N N G G C E Q
Zebra Danio Brachydanio rerio NP_001025352 479 52419 S279 P R G L H S P S A G G D V V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P98069 639 71875 L271 G I W L D T I L P R K D P E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.9 87.1 N.A. 82 82 N.A. N.A. 46.5 21 47.1 N.A. N.A. N.A. N.A. 21.1
Protein Similarity: 100 99.5 97.3 89.9 N.A. 86.7 86.7 N.A. N.A. 62.5 32.5 62 N.A. N.A. N.A. N.A. 32.7
P-Site Identity: 100 100 100 100 N.A. 0 0 N.A. N.A. 13.3 13.3 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 20 20 N.A. N.A. 20 13.3 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 0 10 10 0 40 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 50 20 10 0 0 0 0 0 0 20 0 20 0 % D
% Glu: 10 0 20 10 0 0 0 0 10 0 0 10 0 20 0 % E
% Phe: 0 0 0 0 40 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 10 20 10 40 0 0 0 20 0 10 20 10 0 0 40 % G
% His: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 10 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 50 10 0 0 0 0 % K
% Leu: 0 0 0 20 0 0 0 10 0 0 0 40 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 10 0 0 0 0 % N
% Pro: 30 10 10 0 10 0 10 10 30 0 0 0 50 0 20 % P
% Gln: 0 0 0 0 0 20 0 0 0 20 0 0 0 0 10 % Q
% Arg: 0 10 0 0 0 0 20 0 0 10 0 20 0 40 0 % R
% Ser: 10 0 0 0 0 60 0 60 0 0 20 0 20 0 20 % S
% Thr: 40 0 0 0 0 10 0 0 0 0 40 0 0 0 0 % T
% Val: 0 10 0 0 10 0 10 0 0 0 0 0 10 10 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _