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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD1
All Species:
8.18
Human Site:
T259
Identified Species:
25.71
UniProt:
Q15116
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15116
NP_005009.2
288
31647
T259
V
F
P
S
G
M
G
T
S
S
P
A
R
R
G
Chimpanzee
Pan troglodytes
XP_522790
137
15397
T109
S
Q
P
E
D
S
A
T
Y
L
C
A
F
T
Q
Rhesus Macaque
Macaca mulatta
NP_001107830
288
31676
T259
V
F
P
S
G
L
G
T
S
S
P
A
R
R
G
Dog
Lupus familis
XP_543338
288
31694
P259
T
I
V
F
P
G
R
P
A
S
P
G
R
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q02242
288
31824
A259
V
F
T
E
G
L
G
A
S
A
M
G
R
R
G
Rat
Rattus norvegicus
NP_001100397
287
31874
S259
F
T
E
G
L
D
A
S
A
I
G
R
R
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512994
264
29421
T236
K
P
P
K
T
V
G
T
C
T
S
E
Q
T
E
Chicken
Gallus gallus
XP_422723
281
31307
A250
P
A
E
Q
T
E
Y
A
T
I
V
F
P
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.8
96.1
67
N.A.
59.7
61.1
N.A.
31.2
29.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
30.2
98.2
75.6
N.A.
70.1
70.1
N.A.
46.5
45.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
93.3
26.6
N.A.
53.3
6.6
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
33.3
N.A.
66.6
20
N.A.
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
25
25
25
13
0
38
0
0
13
% A
% Cys:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% C
% Asp:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
25
25
0
13
0
0
0
0
0
13
0
13
25
% E
% Phe:
13
38
0
13
0
0
0
0
0
0
0
13
13
0
0
% F
% Gly:
0
0
0
13
38
13
50
0
0
0
13
25
0
13
38
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
0
0
0
0
25
0
0
0
0
0
% I
% Lys:
13
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
13
25
0
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
13
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
13
50
0
13
0
0
13
0
0
38
0
13
0
0
% P
% Gln:
0
13
0
13
0
0
0
0
0
0
0
0
13
0
13
% Q
% Arg:
0
0
0
0
0
0
13
0
0
0
0
13
63
50
0
% R
% Ser:
13
0
0
25
0
13
0
13
38
38
13
0
0
0
13
% S
% Thr:
13
13
13
0
25
0
0
50
13
13
0
0
0
25
0
% T
% Val:
38
0
13
0
0
13
0
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _