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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDK3
All Species:
40
Human Site:
S28
Identified Species:
88
UniProt:
Q15120
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15120
NP_001135858.1
406
46939
S28
R
F
S
P
S
P
L
S
I
K
Q
F
L
D
F
Chimpanzee
Pan troglodytes
XP_515910
436
49246
S58
R
F
S
P
S
P
L
S
M
K
Q
F
L
D
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537984
415
48052
S28
R
F
S
P
S
P
L
S
I
K
Q
F
L
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q922H2
415
47904
S28
R
F
S
P
S
P
L
S
I
K
Q
F
L
D
F
Rat
Rattus norvegicus
Q63065
434
49063
S58
R
F
S
P
S
P
L
S
M
K
Q
F
L
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514685
394
44811
D17
I
S
P
F
N
P
K
D
L
G
N
Y
F
I
G
Chicken
Gallus gallus
NP_001006259
406
46612
S28
R
F
S
P
S
P
L
S
I
K
Q
F
L
D
F
Frog
Xenopus laevis
NP_001083278
404
46003
S32
R
F
S
P
S
P
L
S
M
K
Q
F
I
D
F
Zebra Danio
Brachydanio rerio
XP_688551
404
46394
S27
R
F
S
P
S
P
L
S
I
K
Q
F
L
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91622
413
46608
S34
G
F
N
P
S
P
L
S
I
K
Q
F
M
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q02332
401
45263
T31
Q
F
Q
P
S
S
L
T
I
Q
Q
Y
L
D
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.5
N.A.
97.1
N.A.
95.1
64
N.A.
63.7
92.8
69.2
82
N.A.
55.9
N.A.
51.4
N.A.
Protein Similarity:
100
77.7
N.A.
97.3
N.A.
96.6
78.3
N.A.
78.5
96.5
81.7
89.6
N.A.
70.2
N.A.
66.2
N.A.
P-Site Identity:
100
93.3
N.A.
100
N.A.
100
93.3
N.A.
6.6
100
86.6
93.3
N.A.
80
N.A.
60
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
93.3
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
82
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
91
0
10
0
0
0
0
0
0
0
82
10
0
91
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
64
0
0
0
10
10
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
82
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
91
0
10
0
0
0
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
28
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
91
0
91
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
10
91
0
0
0
0
% Q
% Arg:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
73
0
91
10
0
82
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _