KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK10
All Species:
30
Human Site:
Y306
Identified Species:
55
UniProt:
Q15131
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15131
NP_001092003.2
360
41038
Y306
L
L
H
F
L
F
M
Y
D
P
K
K
R
A
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546775
360
41038
Y306
L
L
N
F
L
F
M
Y
D
P
K
K
R
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMM4
360
40942
Y306
L
L
N
F
L
F
M
Y
D
P
K
K
R
A
T
Rat
Rattus norvegicus
Q4KM47
358
40615
Y304
L
L
N
F
L
F
M
Y
D
P
K
K
R
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001103409
370
41951
Y314
L
L
N
F
L
F
M
Y
D
P
K
K
R
A
T
Frog
Xenopus laevis
P23437
297
33852
I244
K
S
T
F
P
K
W
I
R
Q
D
F
S
K
V
Zebra Danio
Brachydanio rerio
NP_001017622
275
30997
D222
K
T
Q
T
T
A
L
D
M
W
A
V
G
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPC0
952
108820
Y834
L
L
Q
G
L
L
T
Y
D
P
K
Q
R
L
S
Honey Bee
Apis mellifera
XP_392973
410
46389
Y332
L
L
N
F
L
F
M
Y
D
P
K
K
R
A
T
Nematode Worm
Caenorhab. elegans
Q09437
719
83549
L630
L
L
N
G
L
L
T
L
D
P
K
N
R
F
S
Sea Urchin
Strong. purpuratus
XP_783449
397
44907
Y326
L
L
N
F
L
L
M
Y
N
P
K
K
R
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LFT8
505
56711
L308
L
L
E
K
M
L
V
L
D
P
A
Q
R
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q871M9
545
61347
D311
L
K
E
L
F
K
L
D
W
R
S
R
I
N
A
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
96.9
90.5
N.A.
N.A.
82.9
36.9
60.8
N.A.
21.3
63.9
25.8
63.7
Protein Similarity:
100
N.A.
N.A.
96.9
N.A.
98.8
93.6
N.A.
N.A.
89.7
53.6
69.1
N.A.
27.8
73.6
36.4
75.8
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
6.6
0
N.A.
53.3
93.3
46.6
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
6.6
6.6
N.A.
66.6
100
60
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.4
N.A.
29.7
Protein Similarity:
N.A.
N.A.
N.A.
45.5
N.A.
43.6
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
16
0
0
54
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
16
70
0
8
0
0
0
0
% D
% Glu:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
62
8
47
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
8
% I
% Lys:
16
8
0
8
0
16
0
0
0
0
70
54
0
8
0
% K
% Leu:
85
77
0
8
70
31
16
16
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
8
0
54
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
54
0
0
0
0
0
8
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
77
0
0
0
0
0
% P
% Gln:
0
0
16
0
0
0
0
0
0
8
0
16
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
8
77
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
24
% S
% Thr:
0
8
8
8
8
0
16
0
0
0
0
0
0
0
54
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
8
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _