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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKD1
All Species:
28.18
Human Site:
S549
Identified Species:
62
UniProt:
Q15139
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15139
NP_002733.2
912
101704
S549
P
V
I
P
K
G
S
S
V
G
T
G
T
N
L
Chimpanzee
Pan troglodytes
XP_001170806
912
101668
S549
P
V
I
P
K
G
S
S
V
G
T
G
T
N
L
Rhesus Macaque
Macaca mulatta
XP_001114639
912
101836
S549
P
V
I
P
K
G
S
S
V
G
T
G
T
N
L
Dog
Lupus familis
XP_851386
884
99023
T521
P
V
I
P
K
G
S
T
V
G
S
G
T
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q62101
918
102049
S555
P
V
I
P
K
G
S
S
V
G
S
G
S
N
S
Rat
Rattus norvegicus
Q9WTQ1
918
102025
S555
P
V
I
P
K
G
S
S
V
G
S
G
T
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512992
948
106688
S585
P
V
I
P
K
G
A
S
A
G
S
G
P
N
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685219
878
98838
S515
P
V
I
A
K
G
I
S
Q
G
G
H
H
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61267
476
54243
N161
V
F
K
D
L
S
P
N
E
S
I
G
L
P
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O45818
1070
120565
K742
V
G
G
K
R
I
D
K
L
K
V
P
T
E
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39009
513
58614
D198
T
R
P
V
S
F
F
D
K
Y
L
L
G
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.9
92
N.A.
92.5
93.1
N.A.
81.3
N.A.
N.A.
80.1
N.A.
20.1
N.A.
43.7
N.A.
Protein Similarity:
100
99.5
99.3
93.9
N.A.
95
95.4
N.A.
86.3
N.A.
N.A.
86.7
N.A.
32
N.A.
56.2
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
86.6
N.A.
73.3
N.A.
N.A.
53.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
53.3
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
19
% E
% Phe:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
73
0
0
0
73
10
73
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
73
0
0
10
10
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
10
10
73
0
0
10
10
10
0
0
0
10
0
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
10
10
10
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
73
0
% N
% Pro:
73
0
10
64
0
0
10
0
0
0
0
10
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
55
64
0
10
37
0
10
0
28
% S
% Thr:
10
0
0
0
0
0
0
10
0
0
28
0
55
0
0
% T
% Val:
19
73
0
10
0
0
0
0
55
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _