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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB4
All Species:
14.24
Human Site:
S1068
Identified Species:
34.81
UniProt:
Q15147
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15147
NP_000924.2
1175
134464
S1068
Q
T
Q
Q
L
K
L
S
H
D
R
E
S
K
E
Chimpanzee
Pan troglodytes
XP_001168210
1194
136031
S1068
Q
T
Q
Q
L
K
L
S
H
D
R
E
S
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859719
1175
134489
S1068
Q
T
Q
Q
L
K
L
S
H
D
R
E
S
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B3
1216
138307
K1070
K
E
K
K
E
L
K
K
K
M
D
K
K
R
Q
Rat
Rattus norvegicus
Q9QW07
1175
134478
S1068
Q
T
Q
Q
L
K
L
S
H
D
R
E
S
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
N560
K
S
S
V
I
K
S
N
A
L
S
P
R
W
D
Frog
Xenopus laevis
Q32NH8
758
87399
T681
F
N
P
M
W
Y
E
T
L
H
F
K
I
H
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
K1018
V
Q
N
D
K
T
L
K
T
K
N
E
K
D
R
Honey Bee
Apis mellifera
XP_392528
1074
123813
K997
V
M
N
D
K
T
L
K
T
R
G
I
K
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792233
1188
136094
R1076
Q
L
Q
L
L
A
A
R
N
D
R
E
M
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
98.6
N.A.
40.7
97.7
N.A.
N.A.
22.4
26
N.A.
N.A.
51.7
55
N.A.
61.4
Protein Similarity:
100
97.4
N.A.
99.4
N.A.
59.4
99.1
N.A.
N.A.
35.2
36.6
N.A.
N.A.
68.5
70.9
N.A.
77.1
P-Site Identity:
100
100
N.A.
100
N.A.
0
100
N.A.
N.A.
6.6
0
N.A.
N.A.
13.3
6.6
N.A.
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
40
100
N.A.
N.A.
40
13.3
N.A.
N.A.
13.3
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
50
10
0
0
10
10
% D
% Glu:
0
10
0
0
10
0
10
0
0
0
0
60
0
10
50
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
40
10
0
0
0
10
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
20
0
10
10
20
50
10
30
10
10
0
20
30
50
0
% K
% Leu:
0
10
0
10
50
10
60
0
10
10
0
0
0
0
0
% L
% Met:
0
10
0
10
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
10
20
0
0
0
0
10
10
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
50
10
50
40
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
50
0
10
10
10
% R
% Ser:
0
10
10
0
0
0
10
40
0
0
10
0
40
0
0
% S
% Thr:
0
40
0
0
0
20
0
10
20
0
0
0
0
0
0
% T
% Val:
20
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _