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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB4
All Species:
14.24
Human Site:
S521
Identified Species:
34.81
UniProt:
Q15147
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15147
NP_000924.2
1175
134464
S521
F
K
F
G
N
E
L
S
A
D
D
L
G
H
K
Chimpanzee
Pan troglodytes
XP_001168210
1194
136031
S521
F
K
F
G
N
E
L
S
A
D
D
L
G
H
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859719
1175
134489
S521
Y
K
F
G
N
E
L
S
A
D
D
L
G
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B3
1216
138307
S500
S
S
S
V
F
E
P
S
S
P
G
A
G
E
A
Rat
Rattus norvegicus
Q9QW07
1175
134478
S521
Y
K
F
G
N
E
L
S
A
D
D
F
S
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
H40
H
M
P
F
N
L
A
H
V
K
H
V
F
K
K
Frog
Xenopus laevis
Q32NH8
758
87399
D161
M
N
F
K
E
V
Q
D
L
L
K
M
M
N
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
A498
D
D
D
P
E
E
D
A
S
A
G
K
P
P
E
Honey Bee
Apis mellifera
XP_392528
1074
123813
F477
E
K
H
E
L
E
L
F
R
Q
G
Q
F
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792233
1188
136094
E540
S
S
I
A
A
E
D
E
I
K
L
K
H
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
98.6
N.A.
40.7
97.7
N.A.
N.A.
22.4
26
N.A.
N.A.
51.7
55
N.A.
61.4
Protein Similarity:
100
97.4
N.A.
99.4
N.A.
59.4
99.1
N.A.
N.A.
35.2
36.6
N.A.
N.A.
68.5
70.9
N.A.
77.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
20
80
N.A.
N.A.
13.3
6.6
N.A.
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
26.6
86.6
N.A.
N.A.
20
20
N.A.
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
10
40
10
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
0
0
0
20
10
0
40
40
0
0
0
0
% D
% Glu:
10
0
0
10
20
80
0
10
0
0
0
0
0
10
10
% E
% Phe:
20
0
50
10
10
0
0
10
0
0
0
10
20
0
0
% F
% Gly:
0
0
0
40
0
0
0
0
0
0
30
0
40
0
0
% G
% His:
10
0
10
0
0
0
0
10
0
0
10
0
10
40
0
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
50
0
10
0
0
0
0
0
20
10
20
0
10
50
% K
% Leu:
0
0
0
0
10
10
50
0
10
10
10
30
0
0
10
% L
% Met:
10
10
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
10
0
0
50
0
0
0
0
0
0
0
0
20
0
% N
% Pro:
0
0
10
10
0
0
10
0
0
10
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
20
20
10
0
0
0
0
50
20
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
10
0
0
10
0
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _