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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB4
All Species:
20.61
Human Site:
Y263
Identified Species:
50.37
UniProt:
Q15147
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15147
NP_000924.2
1175
134464
Y263
N
E
I
L
F
P
F
Y
D
A
K
R
A
M
Q
Chimpanzee
Pan troglodytes
XP_001168210
1194
136031
Y263
N
E
I
L
F
P
F
Y
D
A
K
R
A
M
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859719
1175
134489
Y263
N
E
I
L
F
P
F
Y
D
A
K
R
A
M
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B3
1216
138307
L266
N
E
I
L
Y
P
P
L
K
Q
E
Q
V
Q
V
Rat
Rattus norvegicus
Q9QW07
1175
134478
Y263
N
E
I
L
F
P
F
Y
D
A
K
R
A
M
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
Frog
Xenopus laevis
Q32NH8
758
87399
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
Y269
N
E
I
L
Y
P
L
Y
E
E
K
R
C
T
E
Honey Bee
Apis mellifera
XP_392528
1074
123813
Q250
V
M
F
L
N
E
K
Q
R
D
P
T
L
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792233
1188
136094
Y266
N
E
I
L
F
P
M
Y
D
R
E
R
V
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
98.6
N.A.
40.7
97.7
N.A.
N.A.
22.4
26
N.A.
N.A.
51.7
55
N.A.
61.4
Protein Similarity:
100
97.4
N.A.
99.4
N.A.
59.4
99.1
N.A.
N.A.
35.2
36.6
N.A.
N.A.
68.5
70.9
N.A.
77.1
P-Site Identity:
100
100
N.A.
100
N.A.
33.3
100
N.A.
N.A.
0
0
N.A.
N.A.
53.3
6.6
N.A.
66.6
P-Site Similarity:
100
100
N.A.
100
N.A.
53.3
100
N.A.
N.A.
0
0
N.A.
N.A.
73.3
13.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
40
0
0
40
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
10
0
0
0
0
0
% D
% Glu:
0
70
0
0
0
10
0
0
10
10
20
0
0
0
20
% E
% Phe:
0
0
10
0
50
0
40
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
0
50
0
0
0
0
% K
% Leu:
0
0
0
80
0
0
10
10
0
0
0
0
10
10
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
0
0
40
0
% M
% Asn:
70
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
70
10
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
0
10
0
10
50
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
0
60
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
20
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _