KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB4
All Species:
20.91
Human Site:
Y614
Identified Species:
51.11
UniProt:
Q15147
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15147
NP_000924.2
1175
134464
Y614
H
A
I
E
F
V
N
Y
N
K
R
Q
M
S
R
Chimpanzee
Pan troglodytes
XP_001168210
1194
136031
Y614
H
A
I
E
F
V
N
Y
N
K
R
Q
M
S
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_859719
1175
134489
Y614
H
A
I
E
F
V
N
Y
N
K
R
Q
M
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1B3
1216
138307
Y589
S
P
V
E
F
V
E
Y
N
K
M
Q
L
S
R
Rat
Rattus norvegicus
Q9QW07
1175
134478
Y614
H
A
I
E
F
V
N
Y
N
K
R
Q
M
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
R129
I
D
E
V
R
K
R
R
Q
L
S
F
E
G
F
Frog
Xenopus laevis
Q32NH8
758
87399
A250
E
I
A
M
D
L
I
A
R
Y
E
P
S
D
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
N587
F
A
E
S
A
G
M
N
Y
L
K
Q
S
S
I
Honey Bee
Apis mellifera
XP_392528
1074
123813
K566
T
A
G
L
N
Y
L
K
T
Q
A
I
E
F
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792233
1188
136094
Y633
Q
C
I
E
F
V
N
Y
N
K
R
Q
M
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
98.6
N.A.
40.7
97.7
N.A.
N.A.
22.4
26
N.A.
N.A.
51.7
55
N.A.
61.4
Protein Similarity:
100
97.4
N.A.
99.4
N.A.
59.4
99.1
N.A.
N.A.
35.2
36.6
N.A.
N.A.
68.5
70.9
N.A.
77.1
P-Site Identity:
100
100
N.A.
100
N.A.
60
100
N.A.
N.A.
0
0
N.A.
N.A.
20
6.6
N.A.
86.6
P-Site Similarity:
100
100
N.A.
100
N.A.
73.3
100
N.A.
N.A.
0
6.6
N.A.
N.A.
26.6
13.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
10
0
10
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
10
0
20
60
0
0
10
0
0
0
10
0
20
0
0
% E
% Phe:
10
0
0
0
60
0
0
0
0
0
0
10
0
10
10
% F
% Gly:
0
0
10
0
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
50
0
0
0
10
0
0
0
0
10
0
0
10
% I
% Lys:
0
0
0
0
0
10
0
10
0
60
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
10
0
0
20
0
0
10
0
0
% L
% Met:
0
0
0
10
0
0
10
0
0
0
10
0
50
0
0
% M
% Asn:
0
0
0
0
10
0
50
10
60
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
10
10
0
70
0
0
0
% Q
% Arg:
0
0
0
0
10
0
10
10
10
0
50
0
0
0
60
% R
% Ser:
10
0
0
10
0
0
0
0
0
0
10
0
20
70
0
% S
% Thr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% T
% Val:
0
0
10
10
0
60
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
60
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _