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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEC1
All Species:
5.76
Human Site:
S125
Identified Species:
18.1
UniProt:
Q15149
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15149
NP_000436.2
4684
531791
S125
A
V
Q
G
P
L
G
S
P
P
K
R
G
P
L
Chimpanzee
Pan troglodytes
XP_520008
4393
493952
S114
G
L
R
A
E
A
Q
S
P
H
C
A
P
T
P
Rhesus Macaque
Macaca mulatta
XP_001088212
4683
532114
S125
A
V
Q
G
P
L
G
S
P
P
K
R
G
P
L
Dog
Lupus familis
XP_539204
4686
532886
G130
L
S
C
P
P
K
W
G
P
V
P
T
E
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXS1
4691
534197
G131
L
G
C
P
P
K
R
G
P
L
P
A
E
D
P
Rat
Rattus norvegicus
P30427
4687
533521
G131
L
G
C
P
P
K
R
G
P
L
P
A
E
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001093502
4577
522590
V119
K
H
R
Q
V
K
L
V
N
I
R
N
D
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00963
2291
265721
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.7
98.1
92.6
N.A.
93.5
93.5
N.A.
N.A.
N.A.
N.A.
62.1
N.A.
20.5
N.A.
N.A.
N.A.
Protein Similarity:
100
87.4
98.9
96.1
N.A.
96.6
96.5
N.A.
N.A.
N.A.
N.A.
80.2
N.A.
32.5
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
13.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
13
0
13
0
0
0
0
0
38
0
0
0
% A
% Cys:
0
0
38
0
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
13
50
0
% D
% Glu:
0
0
0
0
13
0
0
0
0
0
0
0
38
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
25
0
25
0
0
25
38
0
0
0
0
25
0
0
% G
% His:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
13
% I
% Lys:
13
0
0
0
0
50
0
0
0
0
25
0
0
0
0
% K
% Leu:
38
13
0
0
0
25
13
0
0
25
0
0
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
13
0
0
0
% N
% Pro:
0
0
0
38
63
0
0
0
75
25
38
0
13
25
50
% P
% Gln:
0
0
25
13
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
25
0
0
0
25
0
0
0
13
25
0
0
0
% R
% Ser:
0
13
0
0
0
0
0
38
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% T
% Val:
0
25
0
0
13
0
0
13
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _